Dana-Farber Cancer Institute (DFCI)
Scientist, RNA and Protein Engineering
Dana-Farber Cancer Institute (DFCI), Boston, Massachusetts, us, 02298
Scientist, RNA and Protein Engineering
Dana-Farber Cancer Institute
Boston, MA
Full Time
Overview
RNA-Delivered Antibody-Based Therapy Engineering and Screening – Scientist I
Pre-clinical group developing next generation antibody and CAR T cell immunotherapies for cancer is looking for an exceptionally motivated individual with past lab experience. The group takes projects from conception to transgene design/genetic engineering, through reduction to practice, in vitro and in vivo studies, and ultimately to the clinic. The candidate will make substantial contributions to the planning, execution, and data analysis and should have prior experience with RNA and/or protein engineering. We expect a strong background in some of the laboratory methods required to perform this bench work and we provide training to expand the scientist’s toolbox. Additional opportunities for growth are attending lectures and journal clubs held here at DFCI and participating in academic and industry collaborations. The work is highly translational and there is a clear path to moving to the clinic a candidate based on this work.
We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must.
Responsibilities
Design and perform experiments both individually and collaboratively.
Analyze experimental data and interpret results.
Maintain detailed electronic notebook of all experiments.
Exercise judgment in selecting methods, techniques and evaluation criteria for obtaining results.
Generate data of a quality upon which decisions for the future direction of a program can be based.
Write reports and summaries of findings.
Participate in formal and informal presentations.
Keep up with appropriate literature and research publications.
Develop, modify and improve laboratory procedures.
Contribute to technical reports, the grant application process and manuscript preparation as required.
Operation and maintenance of lab equipment as required.
Proactively contribute to the smooth running of the laboratory.
May direct work and be involved in training of junior staff.
Collaborate and coordinate with team members across groups and functions.
Qualifications
PhD or equivalent. Masters with substantial experience in protein or RNA biochemistry will be considered.
Prior experience with antibody/protein engineering and/or RNA therapies.
We are seeking candidates with at least 2 years of availability.
Exceptionally self-motivated and eager to expand existing skills.
Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
Outstanding organization and detail-oriented.
Must consider attention to detail a strength.
Outstanding planning, organizational, and multi-tasking skills.
Ability to work within a team environment.
Only applicants that submit a cover letter and detailed CV will be considered.
As part of the selection process, the contact information for three references will be requested.
Faculty Director:
Eric Smith, MD PhD ( ericsmithlab.dana-farber.org ).
For more information and to apply, please visit:
careers.dana-farber.org/scientist-rna-protein-engineering
About Dana-Farber Cancer Institute:
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
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Overview
RNA-Delivered Antibody-Based Therapy Engineering and Screening – Scientist I
Pre-clinical group developing next generation antibody and CAR T cell immunotherapies for cancer is looking for an exceptionally motivated individual with past lab experience. The group takes projects from conception to transgene design/genetic engineering, through reduction to practice, in vitro and in vivo studies, and ultimately to the clinic. The candidate will make substantial contributions to the planning, execution, and data analysis and should have prior experience with RNA and/or protein engineering. We expect a strong background in some of the laboratory methods required to perform this bench work and we provide training to expand the scientist’s toolbox. Additional opportunities for growth are attending lectures and journal clubs held here at DFCI and participating in academic and industry collaborations. The work is highly translational and there is a clear path to moving to the clinic a candidate based on this work.
We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must.
Responsibilities
Design and perform experiments both individually and collaboratively.
Analyze experimental data and interpret results.
Maintain detailed electronic notebook of all experiments.
Exercise judgment in selecting methods, techniques and evaluation criteria for obtaining results.
Generate data of a quality upon which decisions for the future direction of a program can be based.
Write reports and summaries of findings.
Participate in formal and informal presentations.
Keep up with appropriate literature and research publications.
Develop, modify and improve laboratory procedures.
Contribute to technical reports, the grant application process and manuscript preparation as required.
Operation and maintenance of lab equipment as required.
Proactively contribute to the smooth running of the laboratory.
May direct work and be involved in training of junior staff.
Collaborate and coordinate with team members across groups and functions.
Qualifications
PhD or equivalent. Masters with substantial experience in protein or RNA biochemistry will be considered.
Prior experience with antibody/protein engineering and/or RNA therapies.
We are seeking candidates with at least 2 years of availability.
Exceptionally self-motivated and eager to expand existing skills.
Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
Outstanding organization and detail-oriented.
Must consider attention to detail a strength.
Outstanding planning, organizational, and multi-tasking skills.
Ability to work within a team environment.
Only applicants that submit a cover letter and detailed CV will be considered.
As part of the selection process, the contact information for three references will be requested.
Faculty Director:
Eric Smith, MD PhD ( ericsmithlab.dana-farber.org ).
For more information and to apply, please visit:
careers.dana-farber.org/scientist-rna-protein-engineering
About Dana-Farber Cancer Institute:
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
#J-18808-Ljbffr