Senior Scientist, Chemistry (BS or MS)

The Chemical Genetics group in Cambridge, MA, is seeking a highly motivated, curious, and innovative scientist to boost our endeavor in the discovery, development, and characterization of small molecules affecting defined phenotypes with the goal of uncovering and validating novel therapeutics and drug targets. We are a highly collaborative and global group of chemists and biologists dynamically exploring the interface of chemistry and biology in initiating, leading, and progressing team-oriented projects in early drug discovery. This group is part of the larger Discovery Sciences (DSc) department that encompasses the full spectrum of sophisticated capabilities needed to succeed in a state-of-the-art drug discovery biopharma laboratory. This position will collaborate closely with research teams within DSc, as well as across diverse Disease Areas.About the Role

Internal Job Title – Senior Scientist IPosition Location: Cambridge, MA, onsiteYour key responsibilities:Applying your chemistry expertise to prosecute on hits from biochemical or phenotypic screens.Small molecule design, multi-step synthesis and optimization, including exploration of structure-activity relationships and synthesis of chemical probes for addressing impactful biological and conceptual questions.Frequent oral data communication/presentation across a spectrum of skillsets and levels, engaging internal and external partners and collaborators.Organizational skills for design, tracking, and communication of experiments and data.A B.S. or M.S. degree in Chemistry and 5+ years of experience in academia or industry, with demonstrated ability in one or more of the following: synthetic organic chemistry, drug discovery, chemical biology, and chemical probe design. This is not a PhD-level position.Proficiency in a broad array of chemical synthesis techniques, chemical probe design and development, characterization, and purification of new molecular entities/modalities. Experience with common spectroscopy (NMR, IR, UV, MS), analytical techniques, and chromatography purification systems is required.A comprehensive knowledge of modern organic synthetic methods; medicinal chemistry and chemical biology knowledge is a plus.Track record of innovation, efficient hypothesis testing, and execution of outside-the-box approaches to tackle challenging scientific problems.Ability to design, perform, analyze, and interpret data to propose next steps in both experimental and project design and overall strategy.Highly self-motivated, fast learner, flexible, innovative, and fearless.Thrives in interdisciplinary, team-oriented, and collaborative environments.Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us!Commitment to Diversity and Inclusion / EEO: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion, or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.Accessibility & Reasonable AccommodationsThe Novartis Group of Companies is committed to working with and providing reasonable accommodation to individuals with disabilities. If you need a reasonable accommodation for any part of the application process or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

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