Pfizer, S.A. de C.V
Senior Principal Scientist-Analytical R&D
Pfizer, S.A. de C.V, Groton, Connecticut, us, 06349
Senior Principal Scientist-Analytical R&D
We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.At Pfizer, we are always seeking to deliver breakthroughs that change patients' lives. In this role, you'll be working to help us achieve that goal by advancing biotechnologically derived products to the market through innovation and delivery of cutting-edge analytical testing. You will be part of a team focused on developing methods and strategies to support product and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, and therapeutic proteins, at all stages of clinical development.ResponsibilitiesApply technical and functional knowledge to design and independently execute experiments/projects, contributing to the overall direction of the project. Technical areas anticipated: HPLC, LC-MS, dissolution, and spectroscopy (IR, NIR, Raman).Act as a scientific resource within own sub-function/therapeutic area/discipline.Develop appropriate drug product analytical control strategies that are aligned with program and regulatory expectations.Provide technical and scientific leadership and represent analytical development on cross-functional and cross-departmental program level teams.Develop assay, qualification, and transfer timelines which align with the program timelines.Manage individual lab work on drug product candidates with a focus on developing analytical methods and strategies to support clinical and commercial aspects of product and process development and controls.Encourage interaction and effective collaboration with project team members, including presenting data at project team meetings; critical review of data; and active involvement in solving technical challenges that arise during development.Ensure that the staff has received appropriate training and that the training is current.Keep abreast of scientific/technological developments by participating in scientific meetings/seminars and through regular scientific review.Present experimental results at group meetings, project meetings, and department meetings.Responsible for the analytical strategies for development of drug product candidates, which may include method development, release and stability testing, characterization and comparability analyses, and analytical support for process and formulation development.Serve as an analytical sciences resource for the department and project teams, proactively keeping colleagues updated with current scientific trends and technical aspects from conferences, local meetings, and literature.Required QualificationsDoctoral Degree (PhD) in Analytical Science.7+ years of experience in drug product pharmaceutical development function.Excellent written communication skills, including the ability to maintain an accurate scientific notebook and draft concise written reports, publications, and related documents.Experienced with multiple software platforms and packages, facilitating large data analytics and visualization.Strong technical skills and scientific expertise in analytical method development and troubleshooting.Additional analytical skills: NMR, particle characterization, forensic analysis preferred.NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTSTravel anticipated to be less than 10%Additional InformationRelocation support available.Work Location Assignment: On PremiseThe annual base salary for this position ranges from $117,300.00 to $195,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share-based long-term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental, and vision coverage.
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We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.At Pfizer, we are always seeking to deliver breakthroughs that change patients' lives. In this role, you'll be working to help us achieve that goal by advancing biotechnologically derived products to the market through innovation and delivery of cutting-edge analytical testing. You will be part of a team focused on developing methods and strategies to support product and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, and therapeutic proteins, at all stages of clinical development.ResponsibilitiesApply technical and functional knowledge to design and independently execute experiments/projects, contributing to the overall direction of the project. Technical areas anticipated: HPLC, LC-MS, dissolution, and spectroscopy (IR, NIR, Raman).Act as a scientific resource within own sub-function/therapeutic area/discipline.Develop appropriate drug product analytical control strategies that are aligned with program and regulatory expectations.Provide technical and scientific leadership and represent analytical development on cross-functional and cross-departmental program level teams.Develop assay, qualification, and transfer timelines which align with the program timelines.Manage individual lab work on drug product candidates with a focus on developing analytical methods and strategies to support clinical and commercial aspects of product and process development and controls.Encourage interaction and effective collaboration with project team members, including presenting data at project team meetings; critical review of data; and active involvement in solving technical challenges that arise during development.Ensure that the staff has received appropriate training and that the training is current.Keep abreast of scientific/technological developments by participating in scientific meetings/seminars and through regular scientific review.Present experimental results at group meetings, project meetings, and department meetings.Responsible for the analytical strategies for development of drug product candidates, which may include method development, release and stability testing, characterization and comparability analyses, and analytical support for process and formulation development.Serve as an analytical sciences resource for the department and project teams, proactively keeping colleagues updated with current scientific trends and technical aspects from conferences, local meetings, and literature.Required QualificationsDoctoral Degree (PhD) in Analytical Science.7+ years of experience in drug product pharmaceutical development function.Excellent written communication skills, including the ability to maintain an accurate scientific notebook and draft concise written reports, publications, and related documents.Experienced with multiple software platforms and packages, facilitating large data analytics and visualization.Strong technical skills and scientific expertise in analytical method development and troubleshooting.Additional analytical skills: NMR, particle characterization, forensic analysis preferred.NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTSTravel anticipated to be less than 10%Additional InformationRelocation support available.Work Location Assignment: On PremiseThe annual base salary for this position ranges from $117,300.00 to $195,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share-based long-term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental, and vision coverage.
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