Rutgers University
Research Associate (Tischfield Lab)
Rutgers University, New Brunswick, New Jersey, us, 08933
Position Information
Recruitment/Posting Title:
Research Associate (Tischfield Lab)Department:
Human Genetics Inst of NJSalary:
Commensurate With ExperiencePosting Summary:
Experienced Research Associate to conduct research on the genetic foundation of Tourette disorder (TD) using genetically engineered mouse models. This research utilizes human data on new mutations that cause TD, recreating those mutations in the orthologous mouse genes. This employee must be fully independent with regard to establishing mouse crosses to produce mice with the proper mutation and genetic background. This individual must be cognizant in mouse behavioral testing as well as newer machine learning approaches. This individual must understand habit/reward selection assays and their application to mice. The individual will do brain histopathology of mutant mice to identify specific cell types and conduct confocal microscopy of sections stained with fluorescent markers for various gene products. Experience with Imaris image analysis software is required. Experience with protein fractionation is highly desired. An understanding and background in human genetics and human neuropsychiatric disorders with a genetic foundation is essential. The ultimate goal is to use mouse models to understand the cellular and molecular bases of TD and for the testing of novel drugs that might provide relief.Position Status:
Full TimePosting Number:
23FA0547Posting Open Date:
[Date not provided]Posting Close Date:
[Date not provided]Qualifications
Minimum Education and Experience:
Doctoral degree in genetics, molecular biology or molecular neuroscience and at least three years of relevant postdoctoral experience with a heavy concentration on mouse behavior and motion sequencing. Training in human and mouse genetics and experience in administering mouse behavioral paradigms is required including data analysis and presentation. Work as part of a team to determine brain circuits altered in TD mice using histopathology, electrophysiology, and optogenetics. Be fully competent in molecular techniques, qPCR, DNA sequencing data analysis, RNA and protein blots, experience with image and data analysis software.Required Knowledge, Skills, and Abilities:
Training in human and mouse genetics and experience in administering mouse behavioral paradigms is required including data analysis and presentation. Work as part of a team to determine brain circuits altered in TD mice using histopathology, electrophysiology, and optogenetics. Be fully competent in molecular techniques, qPCR, DNA sequencing data analysis, RNA and protein blots, experience with image and data analysis software.Equipment Utilized:
Mouse behavioral apparatus including motion sequencing, confocal microscopes, Imaris image analysis software.Physical Demands and Work Environment:
Must be able to work in the mouse facility and in the behavioral testing spaces.Overview
Statement:
This person will collaboratively decide what experiments to do and conduct them in a manner that they individually conceptualize and reduce to practice. They will require the ability to understand data and devise new experiments based on said data. This individual will work as part of a multilevel group consisting of two PIs, other Research Associates, postdoctoral fellows, technicians, and undergraduates. This individual must be capable of supervising technicians and undergraduates.Posting Details
Special Instructions to Applicants:
[Instructions not provided]Quick Link to Posting:
https://jobs.rutgers.edu/postings/201909Campus:
Rutgers University-New BrunswickHome Location Campus:
Busch (RU-New Brunswick)City:
[City not provided]State:
[State not provided]Location Details:
[Details not provided]Pre-employment Screenings
All offers of employment are contingent upon successful completion of all pre-employment screenings.Immunization Requirements
Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination.Affirmative Action/Equal Employment Opportunity Statement
It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, pregnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other category protected by law. As an institution, we value diversity of background and opinion, and prohibit discrimination or harassment on the basis of any legally protected class in the areas of hiring, recruitment, promotion, transfer, demotion, training, compensation, pay, fringe benefits, layoff, termination or any other terms and conditions of employment. For additional information please see the Non-Discrimination Statement at the following web address:
http://uhr.rutgers.edu/non-discrimination-statement .
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Recruitment/Posting Title:
Research Associate (Tischfield Lab)Department:
Human Genetics Inst of NJSalary:
Commensurate With ExperiencePosting Summary:
Experienced Research Associate to conduct research on the genetic foundation of Tourette disorder (TD) using genetically engineered mouse models. This research utilizes human data on new mutations that cause TD, recreating those mutations in the orthologous mouse genes. This employee must be fully independent with regard to establishing mouse crosses to produce mice with the proper mutation and genetic background. This individual must be cognizant in mouse behavioral testing as well as newer machine learning approaches. This individual must understand habit/reward selection assays and their application to mice. The individual will do brain histopathology of mutant mice to identify specific cell types and conduct confocal microscopy of sections stained with fluorescent markers for various gene products. Experience with Imaris image analysis software is required. Experience with protein fractionation is highly desired. An understanding and background in human genetics and human neuropsychiatric disorders with a genetic foundation is essential. The ultimate goal is to use mouse models to understand the cellular and molecular bases of TD and for the testing of novel drugs that might provide relief.Position Status:
Full TimePosting Number:
23FA0547Posting Open Date:
[Date not provided]Posting Close Date:
[Date not provided]Qualifications
Minimum Education and Experience:
Doctoral degree in genetics, molecular biology or molecular neuroscience and at least three years of relevant postdoctoral experience with a heavy concentration on mouse behavior and motion sequencing. Training in human and mouse genetics and experience in administering mouse behavioral paradigms is required including data analysis and presentation. Work as part of a team to determine brain circuits altered in TD mice using histopathology, electrophysiology, and optogenetics. Be fully competent in molecular techniques, qPCR, DNA sequencing data analysis, RNA and protein blots, experience with image and data analysis software.Required Knowledge, Skills, and Abilities:
Training in human and mouse genetics and experience in administering mouse behavioral paradigms is required including data analysis and presentation. Work as part of a team to determine brain circuits altered in TD mice using histopathology, electrophysiology, and optogenetics. Be fully competent in molecular techniques, qPCR, DNA sequencing data analysis, RNA and protein blots, experience with image and data analysis software.Equipment Utilized:
Mouse behavioral apparatus including motion sequencing, confocal microscopes, Imaris image analysis software.Physical Demands and Work Environment:
Must be able to work in the mouse facility and in the behavioral testing spaces.Overview
Statement:
This person will collaboratively decide what experiments to do and conduct them in a manner that they individually conceptualize and reduce to practice. They will require the ability to understand data and devise new experiments based on said data. This individual will work as part of a multilevel group consisting of two PIs, other Research Associates, postdoctoral fellows, technicians, and undergraduates. This individual must be capable of supervising technicians and undergraduates.Posting Details
Special Instructions to Applicants:
[Instructions not provided]Quick Link to Posting:
https://jobs.rutgers.edu/postings/201909Campus:
Rutgers University-New BrunswickHome Location Campus:
Busch (RU-New Brunswick)City:
[City not provided]State:
[State not provided]Location Details:
[Details not provided]Pre-employment Screenings
All offers of employment are contingent upon successful completion of all pre-employment screenings.Immunization Requirements
Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination.Affirmative Action/Equal Employment Opportunity Statement
It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, pregnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other category protected by law. As an institution, we value diversity of background and opinion, and prohibit discrimination or harassment on the basis of any legally protected class in the areas of hiring, recruitment, promotion, transfer, demotion, training, compensation, pay, fringe benefits, layoff, termination or any other terms and conditions of employment. For additional information please see the Non-Discrimination Statement at the following web address:
http://uhr.rutgers.edu/non-discrimination-statement .
#J-18808-Ljbffr