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Massachusetts General Physicians’ Organization

Research Technician II

Massachusetts General Physicians’ Organization, Boston, Massachusetts, us, 02298


Job Description - Research Technician II (3306502)Position Purpose:The MGH Brain Trauma lab uses swine models to understand the development of the immature brain, the pathophysiology of TBI, and post-traumatic sequelae such as post-traumatic epilepsy and hydrocephalus, and to test therapies. Our laboratory applies computational methods including machine learning to investigate the impact of seizures and abnormal brain activity on outcomes in pigs with cortical impact. Our goal is to understand pathological correlates of epilepsy and traumatic brain injury. Analysis of datasets (including video–EEG telemetry, intracellular chloride, among others) is central to these efforts.Key Accountabilities:Performs post-surgical care.May assist with surgery and anesthesia.Collects blood with awake or anesthetized animals. Processes blood per protocols.Identifies, troubleshoots and corrects or recommends solutions to problems associated with experimental methods, procedures and techniques, or equipment and facilities.Ensures adherence to laboratory safety requirements including general and chemical/hazardous waste safety disposal methods.Is encouraged to contribute independently to the scientific content of the experiments, and to author and present original and team-related work.Creates and submits IACUC amendments.Data Collection:Collects data, enters data into databases, animal surgery records, the animals medical record, and data storage devices. Converts paper documents to electronic records.Keeps a detailed laboratory book and electronic notebook recording lab and animal work on a daily basis that is easy for others to read, understand, and repeat the procedures described.Uses Unix Shell (e.g. bash, zsh, etc.), Python, DeepLabCut, SimBA, etc. in a pipeline to classify semiology in videos.Performs basic analyses or interpretation of EEGs.Skills and Knowledge:Background in neuroscience or computer science is strongly recommended.Strong software engineering and quantitative background including knowledge in Python, Unix Shell (e.g. Bash, Zsh, etc), deep neural networks of different architectures (convolutional, recurrent, etc), algorithms (sorting, binary search, etc), C++ or any other compiler based language(s), calculus, basic statistics (hypothesis testing, distributions, regression, etc), data visualization, etc.Experience in animal handling.Ability to work independently with good judgment, organization, attention to detail, and time management skills.Able to work with hands in a sometimes fast-paced environment.Knowledge of neuroanatomy and physiology.Ability to problem-solve and take responsibility in getting things done.Ability to keep organized spreadsheets following existing organizational structures.Willingness to work with/be exposed to hazardous materials such as radioactive materials, infectious materials, and/or hazardous chemicals.Ability to troubleshoot in situations pertaining to operating system environment and software applications.Experience in scientific method and critical thinking.Strong ethical principles.Ability and willingness to employ flexible work hours at various times and to work some nights and weekends as required.Good communication skills to work on a team.While candidates may not have all skills needed, experience in at least some of these methods is favored.Experience:One year of relevant laboratory or science or engineering related experience.Education:Bachelor's degree with a major in a STEM related degree or the equivalent combination of education and experience.Target start date:

November 1st.Massachusetts General Hospital is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

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