MSD
Senior Scientist - Retinal and Vascular Biology
MSD, South San Francisco, California, us, 94083
Job DescriptionOur company's Research Laboratories in South San Francisco is a new innovation hub designed to foster partnership between scientists to discover new medicines to improve human health. The Retinal and Vascular Biology group, a part of the Cardiometabolic Disease Department, is seeking a self-driven and creative Senior Scientist with extensive experience in in vitro and in vivo pharmacology in an industry setting. This is an exciting opportunity for an independent bench scientist to drive assay development and optimization to support drug development, target identification, and validation activities in close partnership with colleagues in the group, department, Research and Development Division South San Francisco, and across the broader company network.The ideal candidate will be an accomplished scientist with a minimum of 5-7 years of industry experience with demonstrated proficiency in in vitro and in vivo assay development and optimization in retinal and/or vascular diseases. This position requires a high level of motivation and dedication to lab experimentation with excellent comprehension of molecular biology, cell signaling pathways, retinal and vascular biology.Education Minimum RequirementBS or MS degree in cell biology, molecular biology, neuroscience, or related biological discipline with a minimum of 8-10 (BS) or 5-7 (MS) years respectively of relevant professional laboratory research experience.
Specific Responsibilities:Employ innovative molecular and cell biology platforms to advance target validation and drug discovery efforts.
Collaborate with multiple stakeholders directly contributing to drug discovery efforts to address high unmet medical needs in retinal and vascular disease.
In vitro and in vivo assay development and optimization in retinal and/or vascular diseases.
Drive assay development and optimization to support drug development, target identification, and validation activities in close collaboration with colleagues in the group, department, Research and Development Division South San Francisco, and across the broader company network.
Required skills:Hands-on experience with building in vitro biochemical and cell-based assays utilizing state-of-art technologies.
Technical expertise and experience in pre-clinical ophthalmology in vivo techniques including FA, OCT, ERG, and ocular injections.
Ability to independently design, conduct, troubleshoot, and analyze experimental data for target identification and validation purposes.
Demonstrated ability to learn, understand, and independently implement new techniques or platforms.
Commitment to experimental excellence and scientific rigor.
Proficiency in using professional data analysis and visualization software such as Spotfire, Excel, and GraphPad Prism.
Excellent oral and written communication and presentation skills.
Strong motivation and passion for science.
Strong technical proficiency in assay development.
High level of organizational skills to support multiple projects in a matrix environment.
Preferred skills:Experience in culturing human endothelial cells.
Experience in handling and processing ex-vivo tissue samples for downstream in vitro analysis.
Knowledge and experience in retinal and/or vascular biology.
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Specific Responsibilities:Employ innovative molecular and cell biology platforms to advance target validation and drug discovery efforts.
Collaborate with multiple stakeholders directly contributing to drug discovery efforts to address high unmet medical needs in retinal and vascular disease.
In vitro and in vivo assay development and optimization in retinal and/or vascular diseases.
Drive assay development and optimization to support drug development, target identification, and validation activities in close collaboration with colleagues in the group, department, Research and Development Division South San Francisco, and across the broader company network.
Required skills:Hands-on experience with building in vitro biochemical and cell-based assays utilizing state-of-art technologies.
Technical expertise and experience in pre-clinical ophthalmology in vivo techniques including FA, OCT, ERG, and ocular injections.
Ability to independently design, conduct, troubleshoot, and analyze experimental data for target identification and validation purposes.
Demonstrated ability to learn, understand, and independently implement new techniques or platforms.
Commitment to experimental excellence and scientific rigor.
Proficiency in using professional data analysis and visualization software such as Spotfire, Excel, and GraphPad Prism.
Excellent oral and written communication and presentation skills.
Strong motivation and passion for science.
Strong technical proficiency in assay development.
High level of organizational skills to support multiple projects in a matrix environment.
Preferred skills:Experience in culturing human endothelial cells.
Experience in handling and processing ex-vivo tissue samples for downstream in vitro analysis.
Knowledge and experience in retinal and/or vascular biology.
#J-18808-Ljbffr