Takeda Pharmaceutical
Research Associate Scientist, Inflammation Discovery Research
Takeda Pharmaceutical, Boston, Massachusetts, United States, 02203
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Job DescriptionAt Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.About the Role:The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a Research Associate Scientist to join our biology and cross-functional discovery teams and create novel drug candidates.Generate and execute preclinical development strategies to support candidate selection, facilitating efficient clinical validation of impactful medicines for patients with inflammatory disorders.Apply deep scientific and technical expertise in immunology and/or cell biology to creatively mature innovative novel concepts within our team, in matrixed collaboration with other Takeda scientists, and external partners.Drive an inclusive, open, and effective culture in a fast-growing drug discovery group.Accountabilities:Generate data packages supporting candidate selection and asset characterization based on current in vitro methods including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models, preferably models that recapitulate cellular cross-talk in fibroinflammatory or diseased tissuesChampion scientific integrity and rigor in preparation and interpretation of detailed protocols/SOPs.Independently plans assignments for a research work group or project, troubleshoots complex problems specialized procedures, and change experimental design if necessary.Develops and validates new methods to support completion of complex assignments within a projectExercises independent judgment (selecting most appropriate methods, coordinating efforts, evaluating criteria for obtaining results)Utilizes technical literature to implement novel procedures, changes, and improvements within a project. Can duplicate and appropriately modify experimental procedures based on the literature.Interprets and analyzes data, helping to incorporate results into overall scientific projects; Independently generates novel hypothesesMaintains a proactive and vocal approach to improving departmental efficiency;Able to summarize and present literature data within the department and occasionally to a broader audienceEducation & Competencies (Technical and Behavioral):MS in a scientific discipline with 3+ years experience, or BS with 5+ years experienceExpertise in at least one of the following assay methods: ELISA/MSD, Western blot, qPCR, flow cytometry, ChIPExperience with cell culture, including isolation, culture, and analysis of primary immune cell subsetsDirect experience with the principles, models, and pathways of autoimmunity, inflammation, and/or fibrosisExperience developing and/or evaluating small molecule, biologic and/or nucleic acid therapeuticsDemonstrates strong organizational and project management skills and effective written and verbal communication skills.Preferred: familiarity with in vivo study design/execution; modern high-dimensional gene expression analysis (i.e., scRNAseq); multicellular culture systems (i.e., organoids)This position is currently classified as onsite in Cambridge, MA.
Takeda Compensation and Benefits Summary
We understand compensation is
an important factor
as you consider the next step in your career. We are committed to
equitable
pay for all employees, and we strive to be more transparent with our pay practices.
For Location:Boston, MAU.S. Base Salary Range:$96,600.00 - $151,800.00The estimated salary range reflects
an anticipated
range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education
attained
, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
?
The actual base salary offered will be
in accordance with
state or local minimum wage requirements for the job location.
U.S. based
e
mployee
s
may be eligible for
s
hort
-
t
erm and/
or
l
ong-
t
erm
incentive
s
.
U.S.
based employees
may be
eligible to
participate
in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and
well-being
benefits, among others. U.S.
based employees are also eligible to receive, per calendar year, up to
80 hours
of sick time, and new hires are eligible to
accrue
up to
120 hours of paid vacation.
EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
LocationsBoston, MA
Worker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time By applying, you consent to your information being transmitted by Jobcase to the Employer, as data controller, through the Employers data processor SonicJobs.See Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions
the information I provide in my application will be processed in line with
Takedas
Privacy Notice
and
Terms of Use .
I further attest that all information I submit in my employment application
is
true to the best of my knowledge.
Job DescriptionAt Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.About the Role:The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a Research Associate Scientist to join our biology and cross-functional discovery teams and create novel drug candidates.Generate and execute preclinical development strategies to support candidate selection, facilitating efficient clinical validation of impactful medicines for patients with inflammatory disorders.Apply deep scientific and technical expertise in immunology and/or cell biology to creatively mature innovative novel concepts within our team, in matrixed collaboration with other Takeda scientists, and external partners.Drive an inclusive, open, and effective culture in a fast-growing drug discovery group.Accountabilities:Generate data packages supporting candidate selection and asset characterization based on current in vitro methods including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models, preferably models that recapitulate cellular cross-talk in fibroinflammatory or diseased tissuesChampion scientific integrity and rigor in preparation and interpretation of detailed protocols/SOPs.Independently plans assignments for a research work group or project, troubleshoots complex problems specialized procedures, and change experimental design if necessary.Develops and validates new methods to support completion of complex assignments within a projectExercises independent judgment (selecting most appropriate methods, coordinating efforts, evaluating criteria for obtaining results)Utilizes technical literature to implement novel procedures, changes, and improvements within a project. Can duplicate and appropriately modify experimental procedures based on the literature.Interprets and analyzes data, helping to incorporate results into overall scientific projects; Independently generates novel hypothesesMaintains a proactive and vocal approach to improving departmental efficiency;Able to summarize and present literature data within the department and occasionally to a broader audienceEducation & Competencies (Technical and Behavioral):MS in a scientific discipline with 3+ years experience, or BS with 5+ years experienceExpertise in at least one of the following assay methods: ELISA/MSD, Western blot, qPCR, flow cytometry, ChIPExperience with cell culture, including isolation, culture, and analysis of primary immune cell subsetsDirect experience with the principles, models, and pathways of autoimmunity, inflammation, and/or fibrosisExperience developing and/or evaluating small molecule, biologic and/or nucleic acid therapeuticsDemonstrates strong organizational and project management skills and effective written and verbal communication skills.Preferred: familiarity with in vivo study design/execution; modern high-dimensional gene expression analysis (i.e., scRNAseq); multicellular culture systems (i.e., organoids)This position is currently classified as onsite in Cambridge, MA.
Takeda Compensation and Benefits Summary
We understand compensation is
an important factor
as you consider the next step in your career. We are committed to
equitable
pay for all employees, and we strive to be more transparent with our pay practices.
For Location:Boston, MAU.S. Base Salary Range:$96,600.00 - $151,800.00The estimated salary range reflects
an anticipated
range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education
attained
, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
?
The actual base salary offered will be
in accordance with
state or local minimum wage requirements for the job location.
U.S. based
e
mployee
s
may be eligible for
s
hort
-
t
erm and/
or
l
ong-
t
erm
incentive
s
.
U.S.
based employees
may be
eligible to
participate
in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and
well-being
benefits, among others. U.S.
based employees are also eligible to receive, per calendar year, up to
80 hours
of sick time, and new hires are eligible to
accrue
up to
120 hours of paid vacation.
EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
LocationsBoston, MA
Worker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time By applying, you consent to your information being transmitted by Jobcase to the Employer, as data controller, through the Employers data processor SonicJobs.See Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions