Flagship Pioneering
ProFound Therapeutics, Inc. | Boston, MA ProFound Therapeutics: Senior Director
Flagship Pioneering, Boston, Massachusetts, us, 02298
ProFound Therapeutics: Senior Director HR
Boston, MA USACompany SummaryProFound Therapeutics is discovering proteins hidden within the expanded human proteome to uncover novel drugs and drug targets, producing first-in-class medicines for a multitude of diseases. The company’s ProFoundry Platform uses state-of-the-art protein detection technologies to systematically identify and validate proteins and dissect their therapeutic potential. The result is an ever-expanding database of tens of thousands of novel proteins, including their connectivity, functionality, and roles in health and disease. ProFound Therapeutics was founded in 2020 by Flagship Pioneering. For more information, please visit
www.profoundtx.com .Position SummaryProFound Therapeutics is looking for a passionate, self-motivated, and dynamic Senior Director of People & Culture to join our rapidly growing biotech company. As a key leader in the People function, you will play a pivotal role in shaping the future of our organization and cultivating a thriving, mission-driven culture. Our leadership team believes that people are the cornerstone of our success, and this role will be instrumental in driving that vision forward.In this role, you will report temporarily to the COO and, eventually, to the Chief People Officer. You will lead the development of the People organization, fostering a workplace that empowers employees to grow, innovate, and contribute to ProFound’s next phase of growth.Operational Transition & OptimizationCollaborate with Flagship’s N2G (NewCo to Growth) transition team to fully transition from corporate HR centers of excellence and establish independent and optimized People systems and processes.Act as a strategic thought partner, translating the company’s people strategy into actionable initiatives while leading operational excellence in HR functions.Talent Training & DevelopmentOversee the creation of world-class talent and development training programs that directly align with ProFound’s mission and objectives.Leverage AI, cutting-edge software, and performance-enhancing tools to drive growth and development across the organization.Build and implement a comprehensive employee development framework, including leadership and management training to strengthen leadership capacity.Revamp performance management practices to support continuous improvement, focusing on agile feedback loops and fostering a culture of growth and accountability.Team Building & RecruitmentTake immediate ownership of the recruitment pipeline in collaboration with the Flagship Talent Acquisition team, ensuring timely and strategic hires.Oversee the recruitment of a junior recruiter (if necessary), while collaborating with the broader Ampersand leadership team to build high-performing teams.Employee Engagement & Company CultureSolidify and embed ProFound’s core values and culture into every aspect of employee interactions, ensuring alignment between cultural goals and day-to-day operations.Play a key leadership role in driving leadership engagement and accountability in fostering and modeling company culture during all phases of the company’s growth.Continuously refine company culture and operating behaviors, ensuring a high level of engagement and alignment with business objectives.Design and implement reward systems that reinforce cultural and behavioral goals, integrating them into the total rewards strategy.Balance strategic vision with hands-on execution, regularly delving into operational details to ensure successful implementation.Entrepreneurial mindset with the ability to operate and make decisions in ambiguous, rapidly changing environments.Strong decision-making capabilities, a fast learner with a bias toward speed and action; inspires team members to operate in a similar manner.Optimistic, solution-focused, and innovative, approaching challenges with a can-do, practical attitude.Transparent and respectful communicator, adept at building relationships and influencing across all levels of the organization.Passionate about culture-building beyond traditional HR model, inspiring personal and professional growth among individuals.High emotional intelligence (EQ), low ego, and a collaborative approach to leadership.Strong proponent of experimentation, embracing new and innovative HR approaches that incorporate both human-centered and AI-driven design.QualificationsBachelor’s degree required; additional HR certifications (SHRM-SCP, SPHR) are a plus.Extensive experience in start-up environments and scaling HR operations, ideally within the biotech or technology sectors.Proven expertise across the full range of HR functions, including talent acquisition, talent management, compliance, HR systems, compensation/benefits, employee relations, and leadership coaching.Ability to manage and execute HR responsibilities in a hands-on manner during the early growth phase.Equal Employment OpportunityFlagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
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Boston, MA USACompany SummaryProFound Therapeutics is discovering proteins hidden within the expanded human proteome to uncover novel drugs and drug targets, producing first-in-class medicines for a multitude of diseases. The company’s ProFoundry Platform uses state-of-the-art protein detection technologies to systematically identify and validate proteins and dissect their therapeutic potential. The result is an ever-expanding database of tens of thousands of novel proteins, including their connectivity, functionality, and roles in health and disease. ProFound Therapeutics was founded in 2020 by Flagship Pioneering. For more information, please visit
www.profoundtx.com .Position SummaryProFound Therapeutics is looking for a passionate, self-motivated, and dynamic Senior Director of People & Culture to join our rapidly growing biotech company. As a key leader in the People function, you will play a pivotal role in shaping the future of our organization and cultivating a thriving, mission-driven culture. Our leadership team believes that people are the cornerstone of our success, and this role will be instrumental in driving that vision forward.In this role, you will report temporarily to the COO and, eventually, to the Chief People Officer. You will lead the development of the People organization, fostering a workplace that empowers employees to grow, innovate, and contribute to ProFound’s next phase of growth.Operational Transition & OptimizationCollaborate with Flagship’s N2G (NewCo to Growth) transition team to fully transition from corporate HR centers of excellence and establish independent and optimized People systems and processes.Act as a strategic thought partner, translating the company’s people strategy into actionable initiatives while leading operational excellence in HR functions.Talent Training & DevelopmentOversee the creation of world-class talent and development training programs that directly align with ProFound’s mission and objectives.Leverage AI, cutting-edge software, and performance-enhancing tools to drive growth and development across the organization.Build and implement a comprehensive employee development framework, including leadership and management training to strengthen leadership capacity.Revamp performance management practices to support continuous improvement, focusing on agile feedback loops and fostering a culture of growth and accountability.Team Building & RecruitmentTake immediate ownership of the recruitment pipeline in collaboration with the Flagship Talent Acquisition team, ensuring timely and strategic hires.Oversee the recruitment of a junior recruiter (if necessary), while collaborating with the broader Ampersand leadership team to build high-performing teams.Employee Engagement & Company CultureSolidify and embed ProFound’s core values and culture into every aspect of employee interactions, ensuring alignment between cultural goals and day-to-day operations.Play a key leadership role in driving leadership engagement and accountability in fostering and modeling company culture during all phases of the company’s growth.Continuously refine company culture and operating behaviors, ensuring a high level of engagement and alignment with business objectives.Design and implement reward systems that reinforce cultural and behavioral goals, integrating them into the total rewards strategy.Balance strategic vision with hands-on execution, regularly delving into operational details to ensure successful implementation.Entrepreneurial mindset with the ability to operate and make decisions in ambiguous, rapidly changing environments.Strong decision-making capabilities, a fast learner with a bias toward speed and action; inspires team members to operate in a similar manner.Optimistic, solution-focused, and innovative, approaching challenges with a can-do, practical attitude.Transparent and respectful communicator, adept at building relationships and influencing across all levels of the organization.Passionate about culture-building beyond traditional HR model, inspiring personal and professional growth among individuals.High emotional intelligence (EQ), low ego, and a collaborative approach to leadership.Strong proponent of experimentation, embracing new and innovative HR approaches that incorporate both human-centered and AI-driven design.QualificationsBachelor’s degree required; additional HR certifications (SHRM-SCP, SPHR) are a plus.Extensive experience in start-up environments and scaling HR operations, ideally within the biotech or technology sectors.Proven expertise across the full range of HR functions, including talent acquisition, talent management, compliance, HR systems, compensation/benefits, employee relations, and leadership coaching.Ability to manage and execute HR responsibilities in a hands-on manner during the early growth phase.Equal Employment OpportunityFlagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
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