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Tempus

Senior Bioinformatics Scientist, MRD

Tempus, Chicago, IL, United States


Passionate about precision medicine and advancing the healthcare industry?Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time for our expanding liquid biopsy portfolio (including diagnostics, therapy selection, molecular residual disease testing and therapeutic response monitoring).We are looking for a highly motivated and capable senior bioinformatics scientist with extensive experience and interest in developing cutting edge assays and algorithms in the oncology (MRD) space. Responsibilities:Develop assays, algorithms, machine learning and statistical models to detect oncology related biomarkers from cell free next-generation sequencing (NGS) dataDesign and conduct analyses applying deep genomic and epigenomic knowledge to derive key insights from large multi-modal datasets Design and execute experiments to characterize performance and support various regulatory submissions.Produce high quality and detailed documentation for all projects.Communicate results with outside scientific teams as well as product and bioinformatics leadership.Lead, mentor and/or train other scientists and engineersQualifications:Must have completed a Ph.D. in Bioinformatics, Computational Biology, Cancer Biology, Genetics, Immunology, Molecular Biology, or Computer ScienceAt least 5 years of postdoc or industry experienceComputational skills using Python and/or RProven experience in developing NGS pipelines using contemporary tools for processing and analyzing NGS data (including epigenetics, DNA, RNA) within a clinical environment.In-depth knowledge of creating statistical models and developing predictive or prognostic algorithmsDemonstrated effective communication and presentation skillsSelf-driven and works well in interdisciplinary teams#LI-SH1#LI-hybridThe expected salary range below is applicable if the role is performed from [New York] and may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits, depending on the position.New York Pay Range$140,000—$180,000 USDThe expected salary range below is applicable if the role is performed from [California] and may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits, depending on the position.California Pay Range$140,000—$180,000 USDWe are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.