GlaxoSmithKline
Oligos Synthesis Lab Head
GlaxoSmithKline, Cambridge, Massachusetts, us, 02140
Site Name:
USA - Massachusetts - Cambridge Posted Date:
Oct 31 2024 Are you driven by the challenge of designing and synthesizing novel oligonucleotide therapeutics? If so, we have the perfect opportunity for you. As our Team Leader, Oligonucleotide Synthesis, you and your team will play a pivotal role in advancing GSK's pre-clinical pipeline through the synthesis, processing, and purification of therapeutic oligonucleotides. Your expertise will enable us to solve complex chemical challenges, pushing the boundaries of what's possible in oligonucleotide therapeutics. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Lead and Innovate:
Establish, lead and develop the therapeutic oligonucleotide synthesis team, collaborating cross-functionally to advance our pre-clinical portfolio and technology platforms. Hire, manage, coach, and develop a high-performing team. Be the Expert:
Serve as GSK's subject matter expert on discovery scale oligonucleotide synthesis. Keep abreast of industry advancements, regulatory requirements and competitor approaches in synthetic oligonucleotide chemistry. Communicate Impact:
Provide regular updates and address challenges to stakeholders at all levels across GSK. Contribute to patents, publications, posters, and presentations, showcasing our scientific advancements. Standardize Excellence:
Develop and maintain standard operating procedures (SOPs) for synthesis, processing, and purification to ensure high-quality, reproducible results. Foster Quality:
Partner with the analytical chemistry team to ensure accountability and excellence in oligonucleotide and conjugate synthesis. Collaborate Externally:
Support partnerships with external entities and manage relationships with CROs. Why you?
Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: BS/MS in Chemistry with 5+ years experience, or Ph.D. in Chemistry with 2+ years' experience, specializing in oligonucleotide synthesis and at least 2+ years in managing laboratory scientists. Experience in modern synthetic chemistry methods, particularly nucleosides, nucleotides, and oligonucleotide synthesis, purification, and analysis. Experience with oligonucleotide conjugation chemistries. Leadership experience, including training, developing, and managing talent and the ability to build, motivate, and inspire diverse high-performing teams. Organic chemistry experience of solving synthetic challenges in the field of therapeutic oligonucleotides. Preferred Qualifications: If you have the following characteristics, it would be a plus: Experience with oligonucleotide conjugation chemistries is desirable. Prior experience of establishing an oligonucleotide synthesis laboratory is a plus. Proven effective communication and negotiation skills suitable for a wide range of audiences, from laboratory analysts to senior management. Demonstrated effective organizational skills, including the ability to set, prioritize, and achieve research goals. Excellent scientific and analytical skills, with a demonstrable ability to multitask, prioritize, and drive projects to conclusion. A demonstrable understanding of RNA biology and contemporary oligonucleotide screening technologies. #LI-GSK . Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
USA - Massachusetts - Cambridge Posted Date:
Oct 31 2024 Are you driven by the challenge of designing and synthesizing novel oligonucleotide therapeutics? If so, we have the perfect opportunity for you. As our Team Leader, Oligonucleotide Synthesis, you and your team will play a pivotal role in advancing GSK's pre-clinical pipeline through the synthesis, processing, and purification of therapeutic oligonucleotides. Your expertise will enable us to solve complex chemical challenges, pushing the boundaries of what's possible in oligonucleotide therapeutics. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Lead and Innovate:
Establish, lead and develop the therapeutic oligonucleotide synthesis team, collaborating cross-functionally to advance our pre-clinical portfolio and technology platforms. Hire, manage, coach, and develop a high-performing team. Be the Expert:
Serve as GSK's subject matter expert on discovery scale oligonucleotide synthesis. Keep abreast of industry advancements, regulatory requirements and competitor approaches in synthetic oligonucleotide chemistry. Communicate Impact:
Provide regular updates and address challenges to stakeholders at all levels across GSK. Contribute to patents, publications, posters, and presentations, showcasing our scientific advancements. Standardize Excellence:
Develop and maintain standard operating procedures (SOPs) for synthesis, processing, and purification to ensure high-quality, reproducible results. Foster Quality:
Partner with the analytical chemistry team to ensure accountability and excellence in oligonucleotide and conjugate synthesis. Collaborate Externally:
Support partnerships with external entities and manage relationships with CROs. Why you?
Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: BS/MS in Chemistry with 5+ years experience, or Ph.D. in Chemistry with 2+ years' experience, specializing in oligonucleotide synthesis and at least 2+ years in managing laboratory scientists. Experience in modern synthetic chemistry methods, particularly nucleosides, nucleotides, and oligonucleotide synthesis, purification, and analysis. Experience with oligonucleotide conjugation chemistries. Leadership experience, including training, developing, and managing talent and the ability to build, motivate, and inspire diverse high-performing teams. Organic chemistry experience of solving synthetic challenges in the field of therapeutic oligonucleotides. Preferred Qualifications: If you have the following characteristics, it would be a plus: Experience with oligonucleotide conjugation chemistries is desirable. Prior experience of establishing an oligonucleotide synthesis laboratory is a plus. Proven effective communication and negotiation skills suitable for a wide range of audiences, from laboratory analysts to senior management. Demonstrated effective organizational skills, including the ability to set, prioritize, and achieve research goals. Excellent scientific and analytical skills, with a demonstrable ability to multitask, prioritize, and drive projects to conclusion. A demonstrable understanding of RNA biology and contemporary oligonucleotide screening technologies. #LI-GSK . Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.