GlaxoSmithKline
Associate Director, Precision Medicine Data & Analytics
GlaxoSmithKline, Waltham, Massachusetts, United States, 02254
Site Name:
USA - Massachusetts - Waltham, USA - Pennsylvania - Upper ProvidencePosted Date:
Oct 9 2024The
Associate Director, Data & Analytics Precision Medicine
position will involve developing clinical biomarker analysis plans in collaboration with biomarker and diagnostic leads, as well as conducting data analysis to summarize and interpret clinical trial data for Clinical Study Reports and regulatory submissions.Key Responsibilities:This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following...Oversee the analysis of complex biological data from clinical trials, ensuring robust interpretation and reporting for Clinical Study Reports and regulatory submissions
Support the delivery of clinical biomarker data analysis to enable Precision Medicine strategies and decision making towards identification of the right patient, right drug, right dose at the right time
Integrate and analyze large-scale, high-dimensional, and multimodal biomarker datasets from internal and external sources to enhance our understanding of mechanisms of action, resistance, patient stratification and selection, new indications, and biologically driven combination strategies.
Collaborate with CPMS, Computational biology, AI/ML, to ensure complementary data analytics approaches are evaluated and applied to deliver the most meaningful insights into the data
Clear and timely communication of data analysis outputs and complex analytical principals & models to matrix team partners
Maintain data integrity principles aligned with human data quality standards
Academic biomarker partnership data and technology evaluation data generated by the Precision Medicine team
Execute internal and external (e.x. real world data) biomarker data analysis to support pipeline growth, including life cycle management plans (e.x. biomarker prevalence in patient populations, right patient/dose), and leveraging data analytics outputs to support decision making.
Execute precision medicine advanced analytics and target/pathway analysis to support evaluation of due diligence business development asset evaluations
Why you?Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:PhD degree or equivalent Computational biology, bioinformatics, machine learning experience/training
5+ years of applied experience in Pharma/Biotech or academic setting.
Experience with coding skills in R and/or Python and good working knowledge of common bioinformatics databases, resources and tools
Prior experience working with infectious diseases and immunology,
Experience communicating analytical principles and results to non-analytical colleagues and stakeholders
Experience in later-stage clinical development (Phase 3) supporting regulatory submissions
Experience working with and analyzing complex high dimensional datasets (e.x. transcriptomics, proteomics, cfDNA) by leveraging state of the art models and analytical approaches
Experience with GCP principals and working on clinical studies
Experience with data and metadata best practices (e.x. FAIR principals, data standards, cloud environment analytical tools)
Experiencing creating data visualization outputs and working with multi-disciplinary teams
Experience with statistical and AI/ML methods relevant to analysis of complex high dimensional heterogeneous datasets
Experience with GitHub, development of R Shiny applications/R markdown, and working in cloud or high-performance computing (HPC) environments is a plus.
#LI-GSKPlease visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
USA - Massachusetts - Waltham, USA - Pennsylvania - Upper ProvidencePosted Date:
Oct 9 2024The
Associate Director, Data & Analytics Precision Medicine
position will involve developing clinical biomarker analysis plans in collaboration with biomarker and diagnostic leads, as well as conducting data analysis to summarize and interpret clinical trial data for Clinical Study Reports and regulatory submissions.Key Responsibilities:This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following...Oversee the analysis of complex biological data from clinical trials, ensuring robust interpretation and reporting for Clinical Study Reports and regulatory submissions
Support the delivery of clinical biomarker data analysis to enable Precision Medicine strategies and decision making towards identification of the right patient, right drug, right dose at the right time
Integrate and analyze large-scale, high-dimensional, and multimodal biomarker datasets from internal and external sources to enhance our understanding of mechanisms of action, resistance, patient stratification and selection, new indications, and biologically driven combination strategies.
Collaborate with CPMS, Computational biology, AI/ML, to ensure complementary data analytics approaches are evaluated and applied to deliver the most meaningful insights into the data
Clear and timely communication of data analysis outputs and complex analytical principals & models to matrix team partners
Maintain data integrity principles aligned with human data quality standards
Academic biomarker partnership data and technology evaluation data generated by the Precision Medicine team
Execute internal and external (e.x. real world data) biomarker data analysis to support pipeline growth, including life cycle management plans (e.x. biomarker prevalence in patient populations, right patient/dose), and leveraging data analytics outputs to support decision making.
Execute precision medicine advanced analytics and target/pathway analysis to support evaluation of due diligence business development asset evaluations
Why you?Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:PhD degree or equivalent Computational biology, bioinformatics, machine learning experience/training
5+ years of applied experience in Pharma/Biotech or academic setting.
Experience with coding skills in R and/or Python and good working knowledge of common bioinformatics databases, resources and tools
Prior experience working with infectious diseases and immunology,
Experience communicating analytical principles and results to non-analytical colleagues and stakeholders
Experience in later-stage clinical development (Phase 3) supporting regulatory submissions
Experience working with and analyzing complex high dimensional datasets (e.x. transcriptomics, proteomics, cfDNA) by leveraging state of the art models and analytical approaches
Experience with GCP principals and working on clinical studies
Experience with data and metadata best practices (e.x. FAIR principals, data standards, cloud environment analytical tools)
Experiencing creating data visualization outputs and working with multi-disciplinary teams
Experience with statistical and AI/ML methods relevant to analysis of complex high dimensional heterogeneous datasets
Experience with GitHub, development of R Shiny applications/R markdown, and working in cloud or high-performance computing (HPC) environments is a plus.
#LI-GSKPlease visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.