Merck
Director, Quantitative Pharmacology and Pharmacometrics (Remote)
Merck, Juneau, Alaska, us, 99812
Director, Quantitative Pharmacology and Pharmacometrics (Remote)
The Quantitative Pharmacology and Pharmacometrics (QP2) Department of our Company's Research Laboratories is seeking a curious and collaborative Director to support our rapidly expanding ophthalmology pipeline.As a director, you will serve as an expert QP2 representative on cross-functional teams of experienced scientists to discover and advance the clinical development of novel therapeutic agents for ophthalmologic disorders. You will work on the discovery and development of small molecules, biologics, and non-traditional therapeutics like peptides. The Director is a skilled quantitative drug developer, with a strong, integrated understanding of the strategic elements of drug discovery and development. The Director should demonstrate outstanding leadership and communication skills and should work independently with minimal supervision.Responsibilities:Develop model-based strategies (translational PK/PD strategies, mechanistic model, POPPK/PD, clinical trial simulations, etc.) for quantitative analyses, to inform and optimize drug discovery and all phases of drug development.Represent QP2 on ophthalmology discovery, early clinical development, and late clinical development teams.Collaborate with other functional areas and external partners, creating an aligned, quantitative, and model-informed regulatory framework.Maintain a comprehensive understanding of global regulatory expectations and shape, present, and defend regulatory documents and submissions.Mentor or supervise early career scientists.Required:(a Ph.D. or equivalent degree with at least seven years of experience) OR (a PharmD or equivalent degree with at least nine years of experience) OR (an MS or equivalent degree with at least 11 years of experience).Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, or a related field.An exemplary record of increasing responsibility in driving drug development decisions.Direct experience in regulatory interactions.Proficiency in written and verbal communication.Preferred:Ability to influence regulatory strategies.Experience in performing population PK/PKPD analyses using standard pharmacometrics software.Expert skills in experimental design, mathematical problem solving, and critical data analysis.Your role at our Company is integral to helping the world meet new breakthroughs that affect generations to come. We’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement.NOTICE FOR INTERNAL APPLICANTSIn accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.Employee Status:
RegularRelocation:
Domestic/InternationalVISA Sponsorship:
YesTravel Requirements:
10%Flexible Work Arrangements:
RemoteJob Posting End Date:
10/31/2024
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The Quantitative Pharmacology and Pharmacometrics (QP2) Department of our Company's Research Laboratories is seeking a curious and collaborative Director to support our rapidly expanding ophthalmology pipeline.As a director, you will serve as an expert QP2 representative on cross-functional teams of experienced scientists to discover and advance the clinical development of novel therapeutic agents for ophthalmologic disorders. You will work on the discovery and development of small molecules, biologics, and non-traditional therapeutics like peptides. The Director is a skilled quantitative drug developer, with a strong, integrated understanding of the strategic elements of drug discovery and development. The Director should demonstrate outstanding leadership and communication skills and should work independently with minimal supervision.Responsibilities:Develop model-based strategies (translational PK/PD strategies, mechanistic model, POPPK/PD, clinical trial simulations, etc.) for quantitative analyses, to inform and optimize drug discovery and all phases of drug development.Represent QP2 on ophthalmology discovery, early clinical development, and late clinical development teams.Collaborate with other functional areas and external partners, creating an aligned, quantitative, and model-informed regulatory framework.Maintain a comprehensive understanding of global regulatory expectations and shape, present, and defend regulatory documents and submissions.Mentor or supervise early career scientists.Required:(a Ph.D. or equivalent degree with at least seven years of experience) OR (a PharmD or equivalent degree with at least nine years of experience) OR (an MS or equivalent degree with at least 11 years of experience).Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, or a related field.An exemplary record of increasing responsibility in driving drug development decisions.Direct experience in regulatory interactions.Proficiency in written and verbal communication.Preferred:Ability to influence regulatory strategies.Experience in performing population PK/PKPD analyses using standard pharmacometrics software.Expert skills in experimental design, mathematical problem solving, and critical data analysis.Your role at our Company is integral to helping the world meet new breakthroughs that affect generations to come. We’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement.NOTICE FOR INTERNAL APPLICANTSIn accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.Employee Status:
RegularRelocation:
Domestic/InternationalVISA Sponsorship:
YesTravel Requirements:
10%Flexible Work Arrangements:
RemoteJob Posting End Date:
10/31/2024
#J-18808-Ljbffr