Xenon Pharmaceuticals Inc.
Senior Director/Executive Director, Development Program Management
Xenon Pharmaceuticals Inc., Boston, Massachusetts, us, 02298
Who We Are:Xenon Pharmaceuticals (NASDAQ:
XENE) is a neuroscience-focused biopharmaceutical company committed to discovering, developing, and commercializing innovative therapeutics to improve the lives of people living with neurological and psychiatric disorders. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team.
What We Do:We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy and depression. Our flagship azetukalner program represents the most advanced potassium channel modulator in clinical development for multiple indications. Building upon the positive results and compelling data from our Phase 2b “X-TOLE” study in adult patients with focal epilepsy, our Phase 3 epilepsy program includes multiple clinical trials evaluating azetukalner in patients with focal onset seizures and primary generalized tonic-clonic seizures. In 2024, we are planning to initiate a Phase 3 azetukalner program in major depressive disorder, based on topline data from our Phase 2 “X-NOVA” clinical trial. In addition, we are proud of the leading-edge science coming out of our discovery labs, including early-stage research programs that leverage our extensive ion channel expertise and drug discovery capabilities to identify validated drug targets and develop new product candidates. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.
About the Role:We are seeking a Senior Director/Executive Director, Development Program Management to lead and manage cross-functional planning of Xenon’s clinical-stage small-molecule drug development programs in both late and early phases with regulatory submissions experience (e.g., INDs, NDAs, MAAs) and life cycle management projects. This role involves close coordination with stakeholders within development (e.g., Clinical Development, Clinical Operations, CMC, Non-Clinical, Regulatory Affairs, Quality) and outside of development (e.g., Finance, Commercial, Legal).This position reports to the Senior Vice President, Portfolio and Alliance Management and will be in Boston, MA, USA. We will consider remote locations for exceptional candidates. The level of the position will be commensurate with the candidate’s education and industry experience.
RESPONSIBILITIES:Overall responsibility to provide strategic and operational expertise as part of the development program management function. This includes working with other leaders within the PM department to define, implement, maintain and continuously improve project standards, processes, metrics, and practices in order to deliver projects and programs according to plan and within budget.Support global product development strategy for Xenon’s products from DTC to product launch including support for commercialization and life cycle management.Create team charters and develop and maintain clear, concise and accurate dashboards for monitoring and communicating program progress to the program team and all levels of the organization, including supporting the development of presentations for Senior Management.Chair, facilitate and coordinate program and/or project meetings and maintain decisions and action items for tracking to completion.Work with the development PM leadership to articulate the 5-year plan and create the development program objectives as part of the Annual Operating Plan (AOP) cycle.Responsible for partnering with functional leaders and key stakeholders to lead the development, implementation and maintenance of high-quality integrated plans for multiple projects or programs addressing program scope, components, schedule, budget, communications, risks, staffing and change management.Ensure cross-functional alignment and accountability on all aspects of program and proactively monitor timelines, milestones, critical path activities and resource needs for assigned programs and/or projects.Support and facilitate resources and financial planning and assessments for programs including working directly with functional leads on assessment of resource timing across programs.Manage program variances and root cause analyses, develop risk mitigation / issue management plans with the objective to meet the timeline and resource targets.Ensure effective, proactive and open communications, to achieve transparency and clarity of program goals, progress and issues. Establish key metrics and monitor performance, through dashboards and reports to enable timely information and analyses for senior leaders.Present to senior leadership, governance teams and external audiences on the project strategy and plans.Develop and propose short- and long-term objectives for the function in accordance with overall company strategies and plans.Plan and manage budget proposals and approved budgets in accordance with the Company’s strategic and operating plans and Finance policies.Recruit, develop, and mentor direct reports, if any, in accordance with the Company’s Human Resource policies and practices.Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports, if any.Other duties as required from time to time.QUALIFICATIONS:Bachelor’s degree or advanced degree in science or business-related field.12+ years of in-depth pharmaceutical industry experience and drug development in a program management capacity in all phases of development with significant experience within related functions (e.g., Clinical Science, Clinical Operations, Research, Regulatory, CMC, Marketing); program management experience reflects leading complex pharmaceutical projects in a multi-disciplinary environment.Demonstrated ability to positively influence outcomes, key project decisions, and strategic problem-solving.Proven ability to communicate clearly and present key information objectively to all levels of the organization including executive management.Matrix program leadership and management skills are required.Ability to influence and negotiate in a matrix environment to optimize development and address barriers.Proactive risk management with ability to propose solutions and deliver appropriate mitigation plan.Ability to communicate (written and verbal) with impact to provide appropriate context, articulate views, drive clarity, and address barriers to progress program development.Ability to drive decision-making within a cross-functional and cross-cultural, global team structure.Ability to inspire and motivate in a matrix and global, cross-geographical team.Excellent organizational skills.Highly effective presentation skills.The base salary range for this role is $246,800 to $295,600 USD; we will consider above this range for exceptional candidates. Base salary is determined by a combination of factors including, but not limited to, education and other qualifications, years of relevant experience, and internal equity.
Our Total Rewards program includes base salary, target bonus, and stock options, as well as a full range of benefits including medical, dental, vision, short-& long-term disability, accidental death & dismemberment, and life insurance programs, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions.Xenon encourages time to rest and re-charge through vacation, personal days, sick days, and an end-of-year company shutdown. Xenon highly values employee development and has an expanding Training, Learning & Development program, including a Tuition Assistance program for advanced degrees.
US positions only:
Xenon Pharmaceuticals USA Inc. participates in the E-Verify program in all states in which we hire. Learn more about the E-Verify program here.To apply for this position, click Apply Now to complete the application. We thank all applicants for their interest; however, due to the volume of applicants, only those chosen for interview will be contacted.#J-18808-Ljbffr
XENE) is a neuroscience-focused biopharmaceutical company committed to discovering, developing, and commercializing innovative therapeutics to improve the lives of people living with neurological and psychiatric disorders. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team.
What We Do:We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy and depression. Our flagship azetukalner program represents the most advanced potassium channel modulator in clinical development for multiple indications. Building upon the positive results and compelling data from our Phase 2b “X-TOLE” study in adult patients with focal epilepsy, our Phase 3 epilepsy program includes multiple clinical trials evaluating azetukalner in patients with focal onset seizures and primary generalized tonic-clonic seizures. In 2024, we are planning to initiate a Phase 3 azetukalner program in major depressive disorder, based on topline data from our Phase 2 “X-NOVA” clinical trial. In addition, we are proud of the leading-edge science coming out of our discovery labs, including early-stage research programs that leverage our extensive ion channel expertise and drug discovery capabilities to identify validated drug targets and develop new product candidates. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.
About the Role:We are seeking a Senior Director/Executive Director, Development Program Management to lead and manage cross-functional planning of Xenon’s clinical-stage small-molecule drug development programs in both late and early phases with regulatory submissions experience (e.g., INDs, NDAs, MAAs) and life cycle management projects. This role involves close coordination with stakeholders within development (e.g., Clinical Development, Clinical Operations, CMC, Non-Clinical, Regulatory Affairs, Quality) and outside of development (e.g., Finance, Commercial, Legal).This position reports to the Senior Vice President, Portfolio and Alliance Management and will be in Boston, MA, USA. We will consider remote locations for exceptional candidates. The level of the position will be commensurate with the candidate’s education and industry experience.
RESPONSIBILITIES:Overall responsibility to provide strategic and operational expertise as part of the development program management function. This includes working with other leaders within the PM department to define, implement, maintain and continuously improve project standards, processes, metrics, and practices in order to deliver projects and programs according to plan and within budget.Support global product development strategy for Xenon’s products from DTC to product launch including support for commercialization and life cycle management.Create team charters and develop and maintain clear, concise and accurate dashboards for monitoring and communicating program progress to the program team and all levels of the organization, including supporting the development of presentations for Senior Management.Chair, facilitate and coordinate program and/or project meetings and maintain decisions and action items for tracking to completion.Work with the development PM leadership to articulate the 5-year plan and create the development program objectives as part of the Annual Operating Plan (AOP) cycle.Responsible for partnering with functional leaders and key stakeholders to lead the development, implementation and maintenance of high-quality integrated plans for multiple projects or programs addressing program scope, components, schedule, budget, communications, risks, staffing and change management.Ensure cross-functional alignment and accountability on all aspects of program and proactively monitor timelines, milestones, critical path activities and resource needs for assigned programs and/or projects.Support and facilitate resources and financial planning and assessments for programs including working directly with functional leads on assessment of resource timing across programs.Manage program variances and root cause analyses, develop risk mitigation / issue management plans with the objective to meet the timeline and resource targets.Ensure effective, proactive and open communications, to achieve transparency and clarity of program goals, progress and issues. Establish key metrics and monitor performance, through dashboards and reports to enable timely information and analyses for senior leaders.Present to senior leadership, governance teams and external audiences on the project strategy and plans.Develop and propose short- and long-term objectives for the function in accordance with overall company strategies and plans.Plan and manage budget proposals and approved budgets in accordance with the Company’s strategic and operating plans and Finance policies.Recruit, develop, and mentor direct reports, if any, in accordance with the Company’s Human Resource policies and practices.Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports, if any.Other duties as required from time to time.QUALIFICATIONS:Bachelor’s degree or advanced degree in science or business-related field.12+ years of in-depth pharmaceutical industry experience and drug development in a program management capacity in all phases of development with significant experience within related functions (e.g., Clinical Science, Clinical Operations, Research, Regulatory, CMC, Marketing); program management experience reflects leading complex pharmaceutical projects in a multi-disciplinary environment.Demonstrated ability to positively influence outcomes, key project decisions, and strategic problem-solving.Proven ability to communicate clearly and present key information objectively to all levels of the organization including executive management.Matrix program leadership and management skills are required.Ability to influence and negotiate in a matrix environment to optimize development and address barriers.Proactive risk management with ability to propose solutions and deliver appropriate mitigation plan.Ability to communicate (written and verbal) with impact to provide appropriate context, articulate views, drive clarity, and address barriers to progress program development.Ability to drive decision-making within a cross-functional and cross-cultural, global team structure.Ability to inspire and motivate in a matrix and global, cross-geographical team.Excellent organizational skills.Highly effective presentation skills.The base salary range for this role is $246,800 to $295,600 USD; we will consider above this range for exceptional candidates. Base salary is determined by a combination of factors including, but not limited to, education and other qualifications, years of relevant experience, and internal equity.
Our Total Rewards program includes base salary, target bonus, and stock options, as well as a full range of benefits including medical, dental, vision, short-& long-term disability, accidental death & dismemberment, and life insurance programs, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions.Xenon encourages time to rest and re-charge through vacation, personal days, sick days, and an end-of-year company shutdown. Xenon highly values employee development and has an expanding Training, Learning & Development program, including a Tuition Assistance program for advanced degrees.
US positions only:
Xenon Pharmaceuticals USA Inc. participates in the E-Verify program in all states in which we hire. Learn more about the E-Verify program here.To apply for this position, click Apply Now to complete the application. We thank all applicants for their interest; however, due to the volume of applicants, only those chosen for interview will be contacted.#J-18808-Ljbffr