Senior Scientist, Medicinal Chemistry

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We are pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With five currently marketed medicines for serious diseases and an expansive late-stage pipeline, we continue to build upon our groundbreaking innovations in science and technology to provide greater value to patients; and we are well positioned financially to deliver on our strategic goals.At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know our success is a direct result of the exceptional talent and dedication of our employees.With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money, and energy into making our onsite and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.We are building on our rich history, and believe our greatest achievements are ahead of us. We invite you to apply and join us if you’re passionate about the opportunity to have meaningful impact on patients in need, our employees, and our organization. Experience and contribute to our unique culture while you develop and expand your career!SENIOR SCIENTIST, MEDICINAL CHEMISTRYWe are looking for a highly motivated individual to join our Medicinal Chemistry team. The successful candidate will play a key role in synthesizing ligands or nucleoside monomers and incorporating them into therapeutic oligonucleotides. This position offers a unique opportunity to work with state-of-the-art technologies and develop cutting-edge skills in the field of RNA therapeutics.REQUIREMENTS:Ph.D. in Organic or Nucleic Acid Chemistry with at least 2 years of post-PHD experienceExtensive experience with purification techniques (e.g., ion exchange, reverse-phase, and size-exclusion chromatography)Experience with automated lab equipment (e.g., NMR, LC-MS)Proven track record of scientific productivity, as evidenced by high-quality publications and/or patentsKnowledge of nucleoside/oligonucleotide synthesis is a plusAbility to be productive and successful in a fast-paced work environmentExcellent communication skills and the ability to thrive in a team settingPlease visit our website,

http://www.ionis.com

, for more information about Ionis and to apply for this position; reference requisition #IONIS003444.Ionis offers an excellent benefits package! Follow this link for more details:

Ionis BenefitsThe pay scale for this position is $122,720 to $145,402.NO PHONE CALLS PLEASE. PRINCIPALS ONLYIonis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

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