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HR Director LLC

Senior Managers, Statistics

HR Director LLC, Conshohocken, Pennsylvania, us, 19429


Job Location: PharmaLex US Corporation, 1 West 1st Avenue, Conshohocken, PA 19428

Job Responsibilities:

Serve as a subject matter expert of clinical biomarkers statistics on statistical methodologies and analysis of data from genomics, transcriptomics, proteomics, and other -omics technologies across all phases of clinical trials;Serve in a Project Lead role by developing scope and cost estimates, allocating resources, and leading project teams to complete projects according to quality assurance, timeline, and budget requirements;Provide strategic planning, statistical support on study/experiment design, and sample size determination for client projects independently or through leading a team;Assess, develop, or recommend statistical/computational methods for predictive, prognostic, and pharmacodynamic biomarkers, pharmacogenomics, companion diagnostics, and other topics independently or through collaboration;Develop statistical programs, shell scripts, reusable functions (or macros) or pipelines, and R Shiny applications in the Windows or Unix/Linux environment (e.g., cloud computing or high-performance computing cluster) and perform peer review or independent programming of analysis conducted by others;Generate or perform critical review of output such as tables, figures, and listings in static formats or interactive HTML reports;Interpret analysis results in both statistical and biological contexts;Communicate with clients at teleconferences, onsite visits, and represent company at scientific conferences or regulatory meetings;Supervise a group of analytical staff members and participate in the hiring process of new employees and serve as a Line Manager to supervise and conduct performance evaluations of direct reports, and provide performance feedback of non-direct team members; andTrain others on knowledge, skills, and tasks as deemed qualified in the areas including, but not limited to, clinical trial statistical reporting, clinical biomarker statistics, and statistical analysis across all phases of clinical trials and applied to a variety of therapeutic areas.

Telecommuting is an option. No in-office presence is required.

Job Requirements:

Employer requires a PhD in Statistics, Data Science, Biostatistics, Computational Biology, Bioinformatics, Computer Science or closely related field and one year of work experience as a statistician or in a related occupation leading and managing projects in the biopharmaceutical consulting industry. In addition, the employer requires the following:

1) Demonstrated ability in performing biomarker statistics, Bayesian statistics, high dimensional data analysis, machine learning and statistical simulations gained through at least one year of work experience.

2) Demonstrated ability developing novel approaches, recommending appropriate statistical models to analyze biomarkers (e.g., predictive, prognostic, pharmacodynamic) and companion diagnostics and interpreting the results in both statistical and biological contexts; and identifying meaningful findings and suggesting value added next steps gained through at least one year of work experience.

3) Demonstrated proficiency in R/SAS programming, Unix/Linux, shell scripting, high performance computing, and cloud computing gained through at least one year of work experience.

4) Demonstrated ability leading multiple projects independently in the biopharmaceutical consulting industry, prioritizing and balancing multiple tasks, supervising and training group of analytical staff and serving as a line manager to at least two reports together gained through at least one year of work experience.

5) Demonstrated ability in understanding and analyzing data of at least one type of -omics data (genomics, transcriptomics or proteomics) gained through at least one year of work experience.

All years of experience may be gained concurrently.

In the a ternative, Employer would accept a Master of Science degree in Statistics, Data Science, Biostatistics, Computational Biology, Bioinformatics, Computer Science or closely related field and at least four years of work experience as a statistician or in a related occupation leading and managing projects in the biopharmaceutical consulting industry. In addition, the employer requires the following:

1) Demonstrated ability in performing biomarker statistics, Bayesian statistics, high dimensional data analysis, machine learning and statistical simulations gained through at least four years of work experience.

2) Demonstrated ability developing novel approaches, recommending appropriate statistical models to analyze biomarkers (e.g., predictive, prognostic, pharmacodynamic) and companion diagnostics and interpreting the results in both statistical and biological contexts; and identifying meaningful findings and suggesting value added next steps gained through at least four years of work experience.

3) Demonstrated proficiency in R/SAS programming, Unix/Linux, shell scripting, high performance computing, and cloud computing gained through at least four years of work experience.

4) Demonstrated ability leading multiple projects independently in the biopharmaceutical consulting industry, prioritizing and balancing multiple tasks, supervising and training group of analytical staff, and serving as a line manager to at least two reports together gained through at least four years of work experience.

5) Demonstrated ability in understanding and analyzing data of at least one type of -omics data (genomics, transcriptomics or proteomics) gained through at least four years of work experience.

All years of experience may be gained concurrently.

This position is eligible for PharmaLex US Corporation's Employee Referral Program.

Applicants can mail resumes to PharmaLex US Corporation, 1 West 1st Avenue Conshohocken, PA 19428 or by email at Heather.Houck@pharmalex.com.