Research Technician I - Beyaz Lab

Position DescriptionCold Spring Harbor Laboratory (CSHL) invites applications for the position of Research Technician-II in the laboratory of Dr. Semir Beyaz. The Beyaz lab is interested in the development of a comprehensive understanding of how nutrients and metabolism influence cellular networks that govern tissue regeneration, cancer and immunity. We dissect the precise mechanisms of how reciprocal interactions between tissue stem cells, immune cells and the microbiome affect tissue fitness or cancer outcomes. We utilize state-of-the-art experimental and computational approaches to integrate genetic, epigenetic, metabolism and microbiome data to identify causal targets that can be therapeutically exploited. To assess therapeutic potential of our discoveries, we have developed a comprehensive and inclusive biobank with tissue specimens, autologous patient-derived organoids and immune cell co-culture systems from patients across diverse ancestries.Position ResponsibilitiesWe are looking for a highly motivated Research Technician-II to join a collaborative team of scientists for developing novel approaches to mitigate toxicity and enhance efficacy of cancer therapeutics. This exciting project is in collaboration with a leading US-based venture capital firm. The successful candidate will have the opportunity to develop new skills in basic science and learn about the process of translating discoveries from bench to bedside.Position RequirementsEducation: A Bachelor's Degree in Biology, Biochemistry, Chemistry or a related discipline and at least two years of research experience is required.Skills and experience: The ideal candidate should have significant experience in molecular biology, mammalian cell culture and mouse models of cancer. Experience in metabolism, epigenetics and cancer therapeutics will be an advantage. The responsibilities include mouse handling and colony management, administration of therapeutic agents to mice, surgical procedures, animal imaging, assessing drug efficacy in 2D cultured cells or 3D organoids-derived from mice or patients, and performing mechanistic experiments. Previous mouse handling experience is a must. Candidates without previous animal experience will not be considered. In addition, the candidate should have strong organizational skills and experience in using and maintaining data spreadsheets. We require a minimum of 2 years commitment to the position.Supplemental InformationHow to Apply:Join us in our mission to uncover the mechanisms that drive health and disease, and make a difference in the field of cancer research! Please submit an online application here:Research Technician- Beyaz Lab Position 01250. We look forward to reviewing your application.Environment:Cold Spring Harbor Laboratory is a world-renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. Cold Spring Harbor Laboratory provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program. We believe that science is for everyone. We have had researchers with a variety of backgrounds and believe in the importance of diversity, equity, and inclusion.Compensation and BenefitsOur employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our CSHL Benefits sites to learn more. The salary range for this role is $45,000-$49,499. The salary range and/or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and/or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity).CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal ContractorCSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability or protected veteran status.Minimum Salary: 45000.00 Maximum Salary: 49449.00 Salary Unit: Yearly