Vertex Pharmaceuticals
Director, Medicinal Chemistry
Vertex Pharmaceuticals, San Diego, California, United States, 92189
Director, Medicinal ChemistryJob Description
The Director, Medicinal Chemistry has an outstanding record of enabling drug candidate identification, refining scientific methods, and/or discovering new targets and diseases for the Vertex portfolio. The successful candidate is viewed as an emerging authority in multiple areas of pharmaceutical discovery and medicinal chemistry. The candidate is versatile and multidimensional with a superior command of knowledge in most areas relevant to his/her/their own area of medicinal chemistry. The Director, Medicinal Chemistry exhibits acumen in directing drug discovery to more productive ends and displays success and/or skills connecting diverse activities to address complicated project goals. A Director may coordinate the activities of multiple Groups when the activities and goals of the Groups overlap. The Director’s responsibilities include the maintenance of organizational balance across the Group(s), as well as setting the scientific directions for personnel. The Director optimizes interdisciplinary understanding and synergy within the Group(s) and integrates activities with those of other Departments and Project Teams, to help shape cohesive Research plans. This is an onsite position at our San Diego research site.
Key Duties & Responsibilities
Manages activities of the Group(s) across Project boundaries
Mentors on scientific and ethical development, motivates personnel, and resolves conflicts
Ensures personnel goal setting is effectively linked to corporate and Department goals
Monitors the activities of staff and provides them insightful guidance to succeed and grow
Assists with hiring for the Group(s) as necessary
Oversees activities of staff and adapts personnel deployment to changing priorities, to ensure key goals of all Projects are met on time
Helps define scientific direction and develops champions of technological innovation for the Group(s)
Directs effective, timely and ethical publication and patenting activities for the Group(s)
Oversees effective management of Group(s)’ CRO activities and/or external scientific collaborations
Maintains high standards for structure and interpretation of all laboratory records, electronic database entries, internal reports, patents and external communications from the Group(s).
Communicates company objectives and resource availability to the Group(s) in a clear and timely manner while developing abilities of others in this role
Leads preparation of clear scientific reports for all other branches and levels of the organization and its collaborators, presents expertly when called upon, and develops abilities of others in this role
Performs other duties as assigned
Required Experience / Required Knowledge/Skills
Established prowess integrating the activities of distinct functional groups across multiple projects in early and late drug discovery
Aptitude for identifying productive new research initiatives/directions; experience in modalities beyond small molecule research is desired (e.g. PROTACs, peptides, oligonucleotides)
Experienced mentor who effectively infuses confidence and team commitment
Exhibits a record of excellent operational and ethical standards and team-improvement
Clear communicator with experience managing across functional areas
Possesses knowledge of multiple drug development paradigms
High distinction achieved resolving important organizational problems and/or infusing innovation
Required Education Level
Ph.D. (or equivalent degree) in chemistry or related science and 9+ years of relevant postdoctoral employment experience, or
Masters Degree (or equivalent degree) in chemistry or related science and 12+ years of relevant employment experience, or
Bachelors Degree (or equivalent degree) in chemistry or related science and 15+ years of relevant employment experience
Pay Range:
$188,000 - $282,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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The Director, Medicinal Chemistry has an outstanding record of enabling drug candidate identification, refining scientific methods, and/or discovering new targets and diseases for the Vertex portfolio. The successful candidate is viewed as an emerging authority in multiple areas of pharmaceutical discovery and medicinal chemistry. The candidate is versatile and multidimensional with a superior command of knowledge in most areas relevant to his/her/their own area of medicinal chemistry. The Director, Medicinal Chemistry exhibits acumen in directing drug discovery to more productive ends and displays success and/or skills connecting diverse activities to address complicated project goals. A Director may coordinate the activities of multiple Groups when the activities and goals of the Groups overlap. The Director’s responsibilities include the maintenance of organizational balance across the Group(s), as well as setting the scientific directions for personnel. The Director optimizes interdisciplinary understanding and synergy within the Group(s) and integrates activities with those of other Departments and Project Teams, to help shape cohesive Research plans. This is an onsite position at our San Diego research site.
Key Duties & Responsibilities
Manages activities of the Group(s) across Project boundaries
Mentors on scientific and ethical development, motivates personnel, and resolves conflicts
Ensures personnel goal setting is effectively linked to corporate and Department goals
Monitors the activities of staff and provides them insightful guidance to succeed and grow
Assists with hiring for the Group(s) as necessary
Oversees activities of staff and adapts personnel deployment to changing priorities, to ensure key goals of all Projects are met on time
Helps define scientific direction and develops champions of technological innovation for the Group(s)
Directs effective, timely and ethical publication and patenting activities for the Group(s)
Oversees effective management of Group(s)’ CRO activities and/or external scientific collaborations
Maintains high standards for structure and interpretation of all laboratory records, electronic database entries, internal reports, patents and external communications from the Group(s).
Communicates company objectives and resource availability to the Group(s) in a clear and timely manner while developing abilities of others in this role
Leads preparation of clear scientific reports for all other branches and levels of the organization and its collaborators, presents expertly when called upon, and develops abilities of others in this role
Performs other duties as assigned
Required Experience / Required Knowledge/Skills
Established prowess integrating the activities of distinct functional groups across multiple projects in early and late drug discovery
Aptitude for identifying productive new research initiatives/directions; experience in modalities beyond small molecule research is desired (e.g. PROTACs, peptides, oligonucleotides)
Experienced mentor who effectively infuses confidence and team commitment
Exhibits a record of excellent operational and ethical standards and team-improvement
Clear communicator with experience managing across functional areas
Possesses knowledge of multiple drug development paradigms
High distinction achieved resolving important organizational problems and/or infusing innovation
Required Education Level
Ph.D. (or equivalent degree) in chemistry or related science and 9+ years of relevant postdoctoral employment experience, or
Masters Degree (or equivalent degree) in chemistry or related science and 12+ years of relevant employment experience, or
Bachelors Degree (or equivalent degree) in chemistry or related science and 15+ years of relevant employment experience
Pay Range:
$188,000 - $282,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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