Bristol Myers Squibb
Associate Director/Sr. Principal Scientist of Translational Medicine
Bristol Myers Squibb, San Diego, California, United States, 92189
Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Summary/Scope
Reporting to Senior Scientific Director Translational Medicine (TM), the TM Associate Director will be part of the late stage TM group. The individual will be responsible for TM and clinical biomarker activities to support drug development programs in neurodegeneration and neuropsychiatric indications. This individual will assume biomarker lead responsibilities such as serving as biomarker representative on study teams, setting up biomarker plans for individual trials and ensuring appropriate collection and timely analysis and reporting of final biomarker data. The individual will also be responsible for answering key TM questions related to the assigned assets and diseases via collaboration with TM laboratory team and/or academic thought leaders. The successful candidate will have prior therapeutic area and late development clinical experience in biotech/pharma organizations interacting with project teams, clinical research physicians, statisticians, computational biologists, contract research organizations and translational scientists to deliver science that supports the development of medicines to patients in need.
Responsibilities will include, but are not limited to, the following:
Designs and implements program-specific late development biomarker/translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable.Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs.Prepares and delivers internal and external translational/biomarker presentations.Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed.Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology.Works with TM laboratory scientists and academic TLs to address nonclinical translational questions.Participates in post-hoc biomarker analysis and publication efforts.Supports regulatory submissions and regulatory interactions as needed.Skills/Knowledge Required
Recognized expertise in translational biomarkers in neurology space.Experience in late stage drug development and activities required for and related to clinical trial initiation, maintenance and completion.Strong verbal and written communication skills.Experience in interacting with CROs and TLs to manage projects and timelines.Proven scientific/leadership expertise (working in teams, mentoring people, managing projects).Accountable for timelines and deliverables.Prioritizes risks and implements contingency plans.Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested.Recognizes cross-functional issues and communicates within the larger organization. Provides expert guidance to multi-disciplinary teams and senior management. Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.Ability to prioritize and manage time efficiently.Accurate and detailed record keeping.Excellent organizational skills.Basic Qualifications:
Bachelor's Degree
12+ years of academic and / or industry experience.
Or Master's Degree
10+ years of academic and / or industry experience.
Or Ph.D. or equivalent advanced degree in the Life Sciences
8+ years of academic and / or industry experience.
4+ years of leadership experience.Preferred Qualifications:
PhD or MD/PhD in neurology related field with 10+ years of translational experience.7+ years of late stage clinical biomarker experience in biotech/pharma.Functional/Scientific/Technical Skills:
Contributing to research program and business.Subject matter leader.Broad knowledge of multiple functional technologies.In-depth understanding of function as it relates to project.Functional area expert with skills, theoretical knowledge and experience to apply scientific direction and approach to projects and problems.Tasks and Responsibilities:
Completes technical assignments by designing, executing and interpreting complex experiments.Recommends department level strategic decisions.May lead scientifically on cross functional assignments.Manages and/or coordinates workflow on projects.Apply diverse scientific knowledge to assignments.Development of research tools.Interpret results.Discretion/Latitude:
Helps design operational strategies consistent with department goals.Provides input and makes recommendations to research strategies.Creativity and Problem Solving:
Identify & solve multi-faceted challenges.Recognizes problems and is able to recommend and develop appropriate solutions from prior experience, literature, or collaboration.Identify risks.Contributes ideas and develops/presents a scientific case (or position) inside and outside department/group.Teamwork and Influence:
Communicates with cross functional team.Directly impacts the achievement of workgroup/team goals.Represents workgroup/team or department on multi-disciplinary or cross functional teams.Work across departments.Organizational Impact:
Direct impact on departmental and asset performance.Impact is achieved by driving team efforts.Able to conceptualize broad impact of research programs and personal activities in terms of site.Behavioral Competencies:
Champions change.Leads courageously.Networking.Provides directions.Structuring and staffing.Thinks strategically.
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Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Summary/Scope
Reporting to Senior Scientific Director Translational Medicine (TM), the TM Associate Director will be part of the late stage TM group. The individual will be responsible for TM and clinical biomarker activities to support drug development programs in neurodegeneration and neuropsychiatric indications. This individual will assume biomarker lead responsibilities such as serving as biomarker representative on study teams, setting up biomarker plans for individual trials and ensuring appropriate collection and timely analysis and reporting of final biomarker data. The individual will also be responsible for answering key TM questions related to the assigned assets and diseases via collaboration with TM laboratory team and/or academic thought leaders. The successful candidate will have prior therapeutic area and late development clinical experience in biotech/pharma organizations interacting with project teams, clinical research physicians, statisticians, computational biologists, contract research organizations and translational scientists to deliver science that supports the development of medicines to patients in need.
Responsibilities will include, but are not limited to, the following:
Designs and implements program-specific late development biomarker/translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable.Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs.Prepares and delivers internal and external translational/biomarker presentations.Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed.Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology.Works with TM laboratory scientists and academic TLs to address nonclinical translational questions.Participates in post-hoc biomarker analysis and publication efforts.Supports regulatory submissions and regulatory interactions as needed.Skills/Knowledge Required
Recognized expertise in translational biomarkers in neurology space.Experience in late stage drug development and activities required for and related to clinical trial initiation, maintenance and completion.Strong verbal and written communication skills.Experience in interacting with CROs and TLs to manage projects and timelines.Proven scientific/leadership expertise (working in teams, mentoring people, managing projects).Accountable for timelines and deliverables.Prioritizes risks and implements contingency plans.Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested.Recognizes cross-functional issues and communicates within the larger organization. Provides expert guidance to multi-disciplinary teams and senior management. Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.Ability to prioritize and manage time efficiently.Accurate and detailed record keeping.Excellent organizational skills.Basic Qualifications:
Bachelor's Degree
12+ years of academic and / or industry experience.
Or Master's Degree
10+ years of academic and / or industry experience.
Or Ph.D. or equivalent advanced degree in the Life Sciences
8+ years of academic and / or industry experience.
4+ years of leadership experience.Preferred Qualifications:
PhD or MD/PhD in neurology related field with 10+ years of translational experience.7+ years of late stage clinical biomarker experience in biotech/pharma.Functional/Scientific/Technical Skills:
Contributing to research program and business.Subject matter leader.Broad knowledge of multiple functional technologies.In-depth understanding of function as it relates to project.Functional area expert with skills, theoretical knowledge and experience to apply scientific direction and approach to projects and problems.Tasks and Responsibilities:
Completes technical assignments by designing, executing and interpreting complex experiments.Recommends department level strategic decisions.May lead scientifically on cross functional assignments.Manages and/or coordinates workflow on projects.Apply diverse scientific knowledge to assignments.Development of research tools.Interpret results.Discretion/Latitude:
Helps design operational strategies consistent with department goals.Provides input and makes recommendations to research strategies.Creativity and Problem Solving:
Identify & solve multi-faceted challenges.Recognizes problems and is able to recommend and develop appropriate solutions from prior experience, literature, or collaboration.Identify risks.Contributes ideas and develops/presents a scientific case (or position) inside and outside department/group.Teamwork and Influence:
Communicates with cross functional team.Directly impacts the achievement of workgroup/team goals.Represents workgroup/team or department on multi-disciplinary or cross functional teams.Work across departments.Organizational Impact:
Direct impact on departmental and asset performance.Impact is achieved by driving team efforts.Able to conceptualize broad impact of research programs and personal activities in terms of site.Behavioral Competencies:
Champions change.Leads courageously.Networking.Provides directions.Structuring and staffing.Thinks strategically.
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