Bristol Myers Squibb
Senior Associate Scientist Discovery Toxicology
Bristol Myers Squibb, San Diego, California, United States, 92189
Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Senior Associate Scientist, Discovery Toxicology
When you join BMS, you are joining a diverse, high-achieving team united by a common mission.
The Pharmaceutical Candidate Optimization organization at Bristol Myers Squibb is a dynamic, multi-disciplinary department that works to discover and optimize new drug candidates. We work across all therapeutic areas and all modalities (small molecules, biotherapeutics, gene and cell therapies and other novel modalities), and engage with all other R&D functions to advance new assets in the BMS portfolio. Our integrated, cross-functional teams apply deep expertise in drug metabolism, pharmacokinetics (DMPK), toxicology, pharmaceutics, and bioanalysis to identify and solve issues, discover high quality drug candidates, and enable their clinical development.
We are seeking an innovative scientist to join the Discovery Toxicology laboratory at BMS San Diego. The Discovery Toxicology team supports the early-stage discovery of pharmaceuticals, including the identification, mechanistic investigation, and risk mitigation from initial target identification through to development candidate nomination. The scientist will serve as an integral member of the Discovery Toxicology team and conduct experiments to support the progression of assets within the discovery portfolio. The successful candidate will be expected to explore and evaluate novel assays and laboratory techniques to expand internal capabilities and contribute to the advancement of toxicology research.
Key Responsibilities
Design, execute, troubleshoot, and interpret in vitro cell culture and molecular biology experimentsDevelop and maintain clear assay protocols and data documentation to facilitate method sharing among scientists in Discovery ToxicologyLearn to conduct analytical assays that can support broad-based mechanistic toxicology investigationsProvide primarily in vitro and occasionally in vivo technical assistance to scientists within Discovery ToxicologyWork collaboratively with functional experts across the organization to successfully execute projectsBasic Qualifications:
Bachelor's degree in biology, pharmacology, immunology, toxicology, or biochemistry with 4 years of academic or industry experience
Or
Master's degree with 2 years academic or industry experience
Preferred Qualifications
Master's degree in biology, pharmacology, immunology, toxicology, or biochemistry with 2 years academic or industry experienceExceptional organizational skills and laboratory/experimental documentation practices are criticalProficient mammalian cell culture skills and aseptic technique are required, experience in primary cell culture and/or 3D tissue culture is preferred but not requiredExperience in molecular biology techniques (e.g., ELISA, western blotting, multiplexed protein analysis, RT-PCR, gene editing, etc.) is requiredExposure working with in vivo mammalian models is required including but not limited to rodent handling, test article administration, animal observation, sample collection, necropsy, data collection and documentation, etc.Ability to work in a collaborative, multidisciplinary team environmentGood written and verbal communication skills are a mustThe starting compensation for this job is a range from $79,000 - $110,000 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site.#J-18808-Ljbffr
Senior Associate Scientist, Discovery Toxicology
When you join BMS, you are joining a diverse, high-achieving team united by a common mission.
The Pharmaceutical Candidate Optimization organization at Bristol Myers Squibb is a dynamic, multi-disciplinary department that works to discover and optimize new drug candidates. We work across all therapeutic areas and all modalities (small molecules, biotherapeutics, gene and cell therapies and other novel modalities), and engage with all other R&D functions to advance new assets in the BMS portfolio. Our integrated, cross-functional teams apply deep expertise in drug metabolism, pharmacokinetics (DMPK), toxicology, pharmaceutics, and bioanalysis to identify and solve issues, discover high quality drug candidates, and enable their clinical development.
We are seeking an innovative scientist to join the Discovery Toxicology laboratory at BMS San Diego. The Discovery Toxicology team supports the early-stage discovery of pharmaceuticals, including the identification, mechanistic investigation, and risk mitigation from initial target identification through to development candidate nomination. The scientist will serve as an integral member of the Discovery Toxicology team and conduct experiments to support the progression of assets within the discovery portfolio. The successful candidate will be expected to explore and evaluate novel assays and laboratory techniques to expand internal capabilities and contribute to the advancement of toxicology research.
Key Responsibilities
Design, execute, troubleshoot, and interpret in vitro cell culture and molecular biology experimentsDevelop and maintain clear assay protocols and data documentation to facilitate method sharing among scientists in Discovery ToxicologyLearn to conduct analytical assays that can support broad-based mechanistic toxicology investigationsProvide primarily in vitro and occasionally in vivo technical assistance to scientists within Discovery ToxicologyWork collaboratively with functional experts across the organization to successfully execute projectsBasic Qualifications:
Bachelor's degree in biology, pharmacology, immunology, toxicology, or biochemistry with 4 years of academic or industry experience
Or
Master's degree with 2 years academic or industry experience
Preferred Qualifications
Master's degree in biology, pharmacology, immunology, toxicology, or biochemistry with 2 years academic or industry experienceExceptional organizational skills and laboratory/experimental documentation practices are criticalProficient mammalian cell culture skills and aseptic technique are required, experience in primary cell culture and/or 3D tissue culture is preferred but not requiredExperience in molecular biology techniques (e.g., ELISA, western blotting, multiplexed protein analysis, RT-PCR, gene editing, etc.) is requiredExposure working with in vivo mammalian models is required including but not limited to rodent handling, test article administration, animal observation, sample collection, necropsy, data collection and documentation, etc.Ability to work in a collaborative, multidisciplinary team environmentGood written and verbal communication skills are a mustThe starting compensation for this job is a range from $79,000 - $110,000 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site.#J-18808-Ljbffr