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Revolution Medicines

Senior Director, Compound Management, Medicinal Chemistry

Revolution Medicines, Redwood City, California, United States, 94061


Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:We are seeking a leader with a strong background in compound management and Lab operations to join our growing team. The successful candidate will work closely with leadership and team members to help grow and maintain a compound management platform. They will be accountable for leading a large cross-functional Compound management, Automation, and Lab management teams.

As a key member of the Medicinal Chemistry Leadership Team, you will make significant contributions to our team with accountability for the following:

Lead all compound management and Chemistry Lab operation functions including compound registration, inventory, storage, reagent inventory, sample tracking, distribution, communication with collaborators, and sample data management.

Establishing strategies that enable growth and expansion of all Compound management, Automation, and Lab management functions.

In close collaboration with Discovery Sciences, Biology, and Pharmacology functions enable further optimization of compound management workflows and expanding HTS screening support.

Work with external partners to further optimize compound archive and storage, distribution, and inventory management with a view to data safety and company growth.

Evaluate and optimize tools that support internal processes and improve user experience. In addition, support changes to software, hardware, and procedures. Proactively seek improvements to usability of these systems and production timelines.

Create and maintain SOPs for critical processes.

Continue customization of sample software and work closely with vendors to solve problems.

Maintain effective oral and written communication to research team members and provide support to ensure timelines are met.

Required Experience, Skills, and Education:

BS/MS or equivalent degree in chemical, biological, engineering sciences or related field with 10+ years working full time in an industrial laboratory setting.

Familiarity with modern compound management and modern data systems preferred.

Proven track record of both compounds and lab management and people leadership across multi-disciplinary drug discovery teams.

Managing, coaching and mentoring scientists across the discovery function in order to develop their skills and build RevMed’s organizational capabilities.

Innovative team-player with high energy for our fast-paced environment.

Strong understanding of chemistry and familiarity with chemistry platforms such as Chemdraw, InstantJChem and Marvin Draw.

Demonstrated ability to plan and achieve research goals as part of an interdisciplinary team.

Excellent written and verbal communication skills to work with interdepartmental teams.

Evidence of successful coaching, mentorship and development of both individuals and teams in order to build long-term organizational capability.

Preferred Skills:

Preferred Experience with Titian Mosaic Sample Bank and its integration with laboratory equipment and software providers.

Preferred Knowledge of SQL databases and SQL/PL/SQL.

The base salary range for this full-time position is $235,000 to $281,000 for candidates based at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the minimum and maximum salary for the position in Redwood City and will be adjusted for the local market a candidate is based. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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