Pfizer
Senior Principal Scientist - Immune Cell Engager
Pfizer, California, Missouri, United States, 65018
Senior Principal Scientist - Immune Cell Engager
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.What You Will Achieve
Pfizer’s Oncology Research Unit (ORU) in La Jolla, California, is seeking a Senior Principal Scientist (PhD) to join the Tumor Immunity team focused on delivering breakthroughs that change patients’ lives by redirecting the immune system against cancer. The Senior Principal Scientist will be responsible for driving scientific strategies and their implementation within a collaborative team of motivated and rigorous scientists to advance immuno-oncology programs within our pre-clinical portfolio.Our ideal candidate will have:A deep expertise in biology, immunology and the development of therapeutic immune (T and/or NK) cell engagersStrong leadership as demonstrated by a track record of building and managing high performing teams of PhD and non-PhD level scientistsExperience in effectively leading cross functional teams within a matrixed environmentThe successful candidate will demonstrate a proven track record of scientific leadership and productivity as evidenced by impact on drug discovery programs and research publications in scientific journals.How You Will Achieve It
Lead research project teams to develop and execute on research strategy and development objectives aligned with ORU strategic focus areasProvide scientific leadership to preclinical project teams serving as the biology lead to design, plan, and execute laboratory experiments and deliver high-quality decision-making data sets in support of project objectives and timelinesFoster and maintain strong collaborative relationships across the ORU discovery organization to design experiments and interpret data sets, driving pipeline advancementsStrengthen department’s overall immuno-oncology capabilities and expertise by employing innovative methods and technologies to test therapeutic hypothesesPresent research findings and share learnings at research project team meetings and research forums and support the development of team members in these settingsManage and mentor scientists in both laboratory based and discipline leadership roles to support preclinical discovery research programs within a matrixed environmentActively contribute to preparation of required drug development and regulatory documents (e.g., IND submissions), with responsibilities for non-clinical pharmacology data packagesEffectively communicate program strategy, methodology, progress, and challenges to multiple stakeholders and partners, including senior executives and governance committeesQualifications
PhD in immunology, cancer biology or relevant biological science with 8+ years of relevant postdoctoral experience.Must have industry experience leading projects through discovery processScientific expertise in immuno-oncology including previous experience with characterization and preclinical development of T and/or NK cell engagersStrong verbal and written communication skillsLeadership experience and capabilities including the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impactDemonstrated success in team management of PhD and non-PhD level scientists, in particular lab based colleaguesCandidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.Relocation support available.Work Location Assignment: On Premise.The annual base salary for this position ranges from $117,300.00 to $195,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.Relocation assistance may be available based on business needs and/or eligibility.Sunshine ActPfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.EEO & Employment EligibilityPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.What You Will Achieve
Pfizer’s Oncology Research Unit (ORU) in La Jolla, California, is seeking a Senior Principal Scientist (PhD) to join the Tumor Immunity team focused on delivering breakthroughs that change patients’ lives by redirecting the immune system against cancer. The Senior Principal Scientist will be responsible for driving scientific strategies and their implementation within a collaborative team of motivated and rigorous scientists to advance immuno-oncology programs within our pre-clinical portfolio.Our ideal candidate will have:A deep expertise in biology, immunology and the development of therapeutic immune (T and/or NK) cell engagersStrong leadership as demonstrated by a track record of building and managing high performing teams of PhD and non-PhD level scientistsExperience in effectively leading cross functional teams within a matrixed environmentThe successful candidate will demonstrate a proven track record of scientific leadership and productivity as evidenced by impact on drug discovery programs and research publications in scientific journals.How You Will Achieve It
Lead research project teams to develop and execute on research strategy and development objectives aligned with ORU strategic focus areasProvide scientific leadership to preclinical project teams serving as the biology lead to design, plan, and execute laboratory experiments and deliver high-quality decision-making data sets in support of project objectives and timelinesFoster and maintain strong collaborative relationships across the ORU discovery organization to design experiments and interpret data sets, driving pipeline advancementsStrengthen department’s overall immuno-oncology capabilities and expertise by employing innovative methods and technologies to test therapeutic hypothesesPresent research findings and share learnings at research project team meetings and research forums and support the development of team members in these settingsManage and mentor scientists in both laboratory based and discipline leadership roles to support preclinical discovery research programs within a matrixed environmentActively contribute to preparation of required drug development and regulatory documents (e.g., IND submissions), with responsibilities for non-clinical pharmacology data packagesEffectively communicate program strategy, methodology, progress, and challenges to multiple stakeholders and partners, including senior executives and governance committeesQualifications
PhD in immunology, cancer biology or relevant biological science with 8+ years of relevant postdoctoral experience.Must have industry experience leading projects through discovery processScientific expertise in immuno-oncology including previous experience with characterization and preclinical development of T and/or NK cell engagersStrong verbal and written communication skillsLeadership experience and capabilities including the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impactDemonstrated success in team management of PhD and non-PhD level scientists, in particular lab based colleaguesCandidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.Relocation support available.Work Location Assignment: On Premise.The annual base salary for this position ranges from $117,300.00 to $195,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.Relocation assistance may be available based on business needs and/or eligibility.Sunshine ActPfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.EEO & Employment EligibilityPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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