Scientist/Senior Scientist, Chemistry

About Willow Biosciences: Willow Biosciences is a synthetic biology company focused on the development of bio-based processes for manufacturing ingredients, including those for consumer care, food & beverage, and pharmaceuticals. Our fully integrated processes are more sustainable, secure, and cost-effective than traditional extraction or chemical synthesis routes and typically provide final products in higher purity.Mission, Values and Beliefs: It is rewarding to work at a company where people genuinely believe in what they are doing. At Willow Biosciences, we are committed to bringing high-purity compounds to market through scalable and cost-effective bio-based processes. We work hard, we are serious about what we do, and we like to have fun while we are at it!Position: Scientist or Senior Scientist, Chemistry: We are seeking a Scientist or Senior Scientist, Chemistry to develop biobased processes for manufacturing high value ingredients. This individual will have a strong organic chemistry background, experience developing biocatalytic and bioconversion processes, and in-depth knowledge of techniques for purification and analysis of target compounds.Location: Sunnyvale, CA, USAEducation:

PhD in chemistry, biochemistry, or a related field with 2 plus years related work experience.Job Description:Design

and execute biocatalytic and bioconversion reactions at bench scaleDevelop

scalable bio-based processes for both bioconversion and isolation and

purification stepsCollaborate

with assay team to implement designed processes in high throughput screening

and evaluate engineered enzymes and strains at bench scaleOffer

strategic recommendations for enzyme and strain engineering and fermentation

process decisionsStructural

characterization of biosynthetically derived molecules and evaluation of

purityDesign,

establish and validate scalable and safe chemical processes leading to

pharmaceutical intermediates, APIs, and other value-added chemical

productsSynthesis

of organic substrates, intermediates, and products as requiredDevelopment

and use of analytical techniques as requiredProper

record-keeping and data analysisPreparation

of documentation for tech transfer of chemical processesWork

closely with manufacturing organizations for scale up of internal

processesEffectively

communicate/present work and analysis to audiences with diverse technical

backgrounds.Evaluate

innovative technologies that will further advance/enable project goalsMentor

research associates/associate scientistsRequired Skills:Experience

developing enzyme-based chemical processes (e.g., biocatalysis,

bioconversions)Strong

knowledge of organic chemistry principles (e.g., chirality, catalysis,

kinetics, thermodynamics, mechanism, synthesis) in addition to strong

organic chemistry skills (e.g., chemical handling, purification, and

analysis)Knowledge

using analytical instrumentation (e.g., HPLC, GC, MS)Knowledge

and ability to solve the structures of unknown compoundsUnderstanding

of process chemistry (e.g., reaction up-scaling, safety, and downstream

processing)Knowledge

of biosynthetic pathways is a plusPhysical Demands:Remaining

in a seated or standing position for extended periodsPerforming

repetitive tasks with hands, fingers, and wristsUse of

standard lab PPE (lab coats, safety glasses and gloves)Position Type:

Full-time positionTravel:

Not requiredWork Authorization : Authorized to work in the USBenefits:Competitive

salary package, 401k, healthcare benefits, medical, vision & dentalPaid

vacation and company holidaysLife /

AD&D, Short-term and Long-term Disability InsuranceOpportunities

for professional developmentEqual Opportunity Employment: Willow Biosciences is an equal opportunity employer. We are committed to creating an inclusive environment for all employees. We do not discriminate based upon race, religion, color, gender, sexual orientation, gender identity, age, status as a protected veteran, status as an individual with a disability, or any other applicable legally protected characteristics. All employment is decided based on qualifications, merit, and business need.

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