Sanofi
Associate Director PKDM
Sanofi, Cambridge, Massachusetts, us, 02140
time left to apply
End Date: November 29, 2024 (9 days left to apply)job requisition id
R2758210About the Job
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s
lives. We’re also
a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
The Pharmacokinetics, Dynamics, and Metabolism (PKDM) department at Sanofi contributes to the safe and effective therapeutic treatment of each patient by applying appropriate pharmacokinetic (PK) and pharmacodynamic (PD) principles to drug development and accelerating the process, where possible. PKDM generates, integrates, and leverages clinical and non-clinical PK, PK/PD and metabolism knowledge to support critical decision making and risk management for projects from first in human dosing through life cycle management. As such, we aid in dose selection/study design, de-risking of drug-drug interactions, benefit/risk assessment, and formulation development, with the use of Population PK, PK/PD, and PBPK approaches as appropriate, and contribute to regulatory
submissions/interactions.Job Summary:PKDM at Sanofi is seeking a dynamic individual to serve as a PK/PD expert participating in multidisciplinary teams for clinical phase development projects in different therapeutic areas. This position will be based in Cambridge, MA.Serves as a PKDM representative on project team(s) and works in close collaboration with multidisciplinary team to progress drug candidates from IND through early phase/late phase to successful approval.Responsible for the design, planning and oversight of relevant studies, as well as PK/PD analysis, interpretation, and reporting of results for molecules/compounds in clinical stage.Applies quantitative skills, via modeling and simulation, to provide dose selection and complex issues at various stages of drug development.Responsible for clinical pharmacology contributions to regulatory documents and inquiries.Interfaces with Research and works closely with discovery research during the pre-IND stages of drug development to ensure sufficient PK/PD knowledge exists for translation to the clinic.About youBasic QualificationsMinimum 5 years of experience in clinical PK/PD, pharmacometrics, and/or clinical pharmacologyProficient in PK modeling software/platforms.Effective communication and interpersonal skills.Strong presentation skills; good team player.EducationPh.D. degree in clinical pharmacology, pharmacokinetics, pharmacometrics, mathematics, engineering, computational biology or a related field required, with or without post-doctoral experience plus 5 years of relevant experienceMS/MA
degree in clinical pharmacology, pharmacokinetics, pharmacometrics, mathematics, engineering, computational biology or a related field required
plus at least 12 years of relevant experienceBS/BA
degree in clinical pharmacology, pharmacokinetics, pharmacometrics, mathematics, engineering, computational biology or a related field required
plus at least 14 years of relevant experienceWhy Choose Us?Bring the miracles of science to life alongside a supportive, future-focused team.Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.#GD-SG#LI-GZ#LI-Onsite#vhdPDNBetter is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.time left to apply
End Date: November 29, 2024 (9 days left to apply)time left to apply
End Date: January 10, 2025 (30+ days left to apply)About Us
Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com
or via our movie
We are SanofiWhy Sanofi
As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live.
#J-18808-Ljbffr
End Date: November 29, 2024 (9 days left to apply)job requisition id
R2758210About the Job
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s
lives. We’re also
a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
The Pharmacokinetics, Dynamics, and Metabolism (PKDM) department at Sanofi contributes to the safe and effective therapeutic treatment of each patient by applying appropriate pharmacokinetic (PK) and pharmacodynamic (PD) principles to drug development and accelerating the process, where possible. PKDM generates, integrates, and leverages clinical and non-clinical PK, PK/PD and metabolism knowledge to support critical decision making and risk management for projects from first in human dosing through life cycle management. As such, we aid in dose selection/study design, de-risking of drug-drug interactions, benefit/risk assessment, and formulation development, with the use of Population PK, PK/PD, and PBPK approaches as appropriate, and contribute to regulatory
submissions/interactions.Job Summary:PKDM at Sanofi is seeking a dynamic individual to serve as a PK/PD expert participating in multidisciplinary teams for clinical phase development projects in different therapeutic areas. This position will be based in Cambridge, MA.Serves as a PKDM representative on project team(s) and works in close collaboration with multidisciplinary team to progress drug candidates from IND through early phase/late phase to successful approval.Responsible for the design, planning and oversight of relevant studies, as well as PK/PD analysis, interpretation, and reporting of results for molecules/compounds in clinical stage.Applies quantitative skills, via modeling and simulation, to provide dose selection and complex issues at various stages of drug development.Responsible for clinical pharmacology contributions to regulatory documents and inquiries.Interfaces with Research and works closely with discovery research during the pre-IND stages of drug development to ensure sufficient PK/PD knowledge exists for translation to the clinic.About youBasic QualificationsMinimum 5 years of experience in clinical PK/PD, pharmacometrics, and/or clinical pharmacologyProficient in PK modeling software/platforms.Effective communication and interpersonal skills.Strong presentation skills; good team player.EducationPh.D. degree in clinical pharmacology, pharmacokinetics, pharmacometrics, mathematics, engineering, computational biology or a related field required, with or without post-doctoral experience plus 5 years of relevant experienceMS/MA
degree in clinical pharmacology, pharmacokinetics, pharmacometrics, mathematics, engineering, computational biology or a related field required
plus at least 12 years of relevant experienceBS/BA
degree in clinical pharmacology, pharmacokinetics, pharmacometrics, mathematics, engineering, computational biology or a related field required
plus at least 14 years of relevant experienceWhy Choose Us?Bring the miracles of science to life alongside a supportive, future-focused team.Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.#GD-SG#LI-GZ#LI-Onsite#vhdPDNBetter is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.time left to apply
End Date: November 29, 2024 (9 days left to apply)time left to apply
End Date: January 10, 2025 (30+ days left to apply)About Us
Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com
or via our movie
We are SanofiWhy Sanofi
As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live.
#J-18808-Ljbffr