Associate Director - Skeletal Diseases in Vivo Lead

We are seeking an Associate Director with extensive hands-on in vivo experience in the skeletal diseases field. The successful candidate must be proficient with in vivo methods as well as rodent surgical methods. Duties and Responsibilities: Effectively collaborate with both internal and external scientists on completion of skeletal diseases field in vivo studies which includes CRO study placement/monitoring. Managing in vivo study projects including study design, sizing of cohorts, dosing, application of in vivo testing modalities, tissue collection, sample management, animal model selection, data analysis including statistics application, authoring study reports, and interpretation/presentation of scientific results. Provide projection on study project needs including budgeting, staffing, and scheduling. Execute hands-on responsibilities including, but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. Communicate experimental plans and results to the leadership team. Support product development and regulatory filings for pivotal clinical studies. Providing daily care and monitoring of mice or rats, including health checks and documentation, will also be required. Effectively collaborate with other in vivo leads from other therapeutic areas to ensure portfolio project study prioritization. This includes working with other units to share equipment and staffing as needed. Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation. Training technical staff on all aspects of in vivo study management. Oversight of in vivo technical staff performance of in vivo studies in the skeletal diseases area. Responsible for scheduling of study technical staff to ensure timely completion of in vivo studies. Responsible for oversight of accuracy of technical staff data collection and analysis. Requirements: Demonstrated experience in skeletal biology/disease research in academia or industry (preferred) including publication record. Experience in breeding colony management and familiarity with mouse model creation processes and techniques (e.g. CRISPR, Cre-lox and Tet-on systems, mouse IVF concepts) and familiarity with mutant model types (transgenic, knockout and knock-in models, conditional and traditional mutant lines) is highly desired Strong understanding of genetically engineered models, breeding, and management and Gene therapy modalities. Passion for contributing your scientific skills to develop therapies for patients in need. Qualifications: PhD in a related subject area with demonstrated research experience in skeletal biology 7 years of Postdoctoral or previous industry experience in skeletal biology Extensive hands-on experience with rodent in vivo work. Previous in vivo staff management experience.