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Regeneron Pharmaceuticals, Inc.

Vice President, Molecular Profiling Computational Data Sciences

Regeneron Pharmaceuticals, Inc., Tarrytown, New York


Seeking experienced, rigorous, and innovative leader to head Regenerons Molecular Profiling Computational Data Sciences research team, consisting of approximately 35 dynamic researchers supporting all therapeutic areas, core technology groups and clinical development units at Regeneron in the design, generation and interpretation of high dimensional data sets from key platform technologies such as single cell RNA sequencing, bulk RNA sequencing, TCR/BCR sequencing and spatial transcriptomics. The position plays a key role in furthering Regenerons ability to advance our understanding of novel targets and biological pathways from discovery to clinical development. Successful candidate would direct and inspire the Data Sciences team by using their deep and broad expertise in the computational biological sciences to set strategic vision, suggest novel technological approaches, and critically evaluate data and projects. Candidate would be expected to participate in translational activities, progressing drug targets along the pipeline from early research through clinical development. Candidate would also participate in Regenerons broader scientific community, participating actively in cross-functional meetings and representing Regenerons Molecular Profiling Computational Data sciences vision to Senior Leadership and external collaborators. As a Vice President at Regeneron a typical day might look like: Directly supervise Regenerons senior Molecular profiling Data science team and manage the broader group, providing vision, inspiration, and both short-term and long-term goals. Communicate priorities, policies, and goals of Regeneron Senior Leadership to the group. Identify new strategies, computational tools or technologies, including genetic medicines and gene therapies, for pursuing novel targets and approaches. Set priorities and ensure progression of, or go/no-go decisions for, research targets and projects within the Data Sciences Group. Be familiar with processes and procedures for moving targets from preclinical research through the development pipeline. Actively participate in departmental, cross-functional, senior leadership, and external meetings to contribute genomic expertise and to represent the goals and vision of the Data Sciences group. Work collaboratively with the Research IT group to develop and populate interfaces to allow non-bioinformatician scientists to easily and intuitively query large public and proprietary RNAseq and other omits datasets to enable target discovery and the development of targeted therapies. Interact broadly and collaboratively with other therapeutic focus areas and technology groups within the company, forging relationships and active collaborations, as well as leveraging technologies to advancing our research portfolio. Lead and mentor the Molecular Profiling Data Sciences Group, providing opportunities, visibility, and challenge in order to develop all group members to their maximum scientific and professional potential. Conduct or oversee review of genomic-related documents, including regulatory submissions, manuscripts, contracts, etc. Interact collaboratively with peer colleagues in the Regeneron Genetics Center and Corporate IT This Role Might Be For You If You Have Both deep and broad expertise in the field of computational biology and quantitative sciences. Experience in bioinformatic processing of Cas9 and other genetic screens Ability to aid in promoter design for gene therapy In addition, expertise in the selection of lead templates from various gene therapy modalities (siRNA, shRNA) and delivery systems (viral and non-viral) would be desirable. Familiarity with cutting edge technologies and next generation sequencing platforms with a proven experience of applying technologies to biomedical research related questions essential. Strong written and oral communication skills with the ability to communicate both science and vision essential. Strong leadership skills with managerial and mentorship experience and excellence essential. Experience with administratively directing a large group (managing budget and organization, etc.) is essential. Exposure to drug development or similar regulated activities highly desirable. Broad network of colleagues and collaborators, strong publication record, and national/international reputation is desirable. At least 10 years experience after PhD; 20 years desirable; a minimum of 8 years in an industry or translational setting. Does this sound like you? Apply now to take your first step towards living the Regeneron Way We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $300,000.00 - $500,000.00