Senior Research Associate II, Inflammation Biology

Senior Research Associate II, Inflammation Biology United States - California - Foster City Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions. Making an impact on a global scale Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly CreatingPossible For Current Gilead Employees and Contractors: Please log onto your Internal Career Site to apply for this job. At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description We are seeking a highly motivated Senior Research Associate to join our inflammation group. The candidate will be responsible for evaluating novel therapeutics in pre-clinical models of autoimmune and inflammatory diseases. Hands-on experience and knowledge of preclinical models of inflammatory autoimmune diseases is required. The successful candidate will be responsible for execution of in vivo mouse studies, ex vivo phenotyping of tissues and generating and communicating pharmacology data of preclinical models internally to support inflammatory target discovery for autoimmunity. Primary responsibilities: Designing, conducting, analyzing and reporting in vivo studies (efficacy, PK/PD). Pre-clinical model development, optimization, and characterization. Ex vivo phenotyping of the immune response, using techniques such as animal tissue processing to isolate immune cells, multicolor flow cytometry to assess immune cell phenotype and function, gene expression profiling and ELISA. Coordinating shipment of ex vivo samples as needed. Interface with cross-functional project team members, and participation in and presentation at project team meetings and cross-departmental team meetings. Qualifications & prior experience: Bachelors or M.S. in Biology or Pharmacology related discipline. 2-4 years of research experience in an industry setting or academic research institution with understanding of inflammatory disease pathogenesis. Hand-on research experience with mouse models of inflammation and proficiency with various mouse handling techniques including dosing (IV, PO, subcutaneous, IP), preclinical manifestation scoring (e.g., joint swelling, paralysis), and collection and handling of tissues during necropsy and processing for ex vivo analysis. Experience with processing tissues for flow cytometry and flow cytometric analysis is required. Excellent organizational and communication skills, along with the ability to work effectively in a multidisciplinary team environment. The ability to work independently on day-to-day responsibilities and research goals along with strong attention to detail. The salary range for this position is: $107,270.00 - $138,820.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. For jobs in the United States: As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodationsgilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please log onto your Internal Career Site to apply for this job. jeid-eba26a6df89bc7499680c53382f3b8e7