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AbbVie

Senior Scientist II Cell & Molecular Biology (Dermatology)

AbbVie, Irvine, California

Salary: $103,500 - $197,000


Company Description At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit www.AllerganAesthetics.com . Job Description Allergan Aesthetics R&D, Biological Research is seeking a highly motivated and innovative candidate for the role of Sr Scientist II Cell and Molecular Biology. The successful candidate will lead and contribute to the discovery and validation of targetsin medical aesthetics, by developing and deploying cell and molecular biology techniques to evaluate therapeutic targets and testable hypotheses.He/she/they willparticipate in a team of scientists to lead and conduct various activities including target identification/validation and drug discovery using iPSC-derived cell systems, in vitro, ex vivo, -omics methodologies to evaluate pharmacology in collaboration with internal and external stake holders/experts. Prior experience in vitro models of the skin and/or hair are highly desired. The candidate shouldbe a highly motivated, hands-on experimentalist who is also capable to leading scientific projects and thriving in a multidisciplinary environment. Emphasis is on the ability to successfully perform hands-on work and lead discovery projects with minimal supervision, demonstrate scientific leadership skills and interact in a team environment. Key Responsibilities Lead and implement molecular and cell biology models to support target validation and progression of early-stage targets in medical aesthetics. iPSC culture and differentiation strategy and execution for hair follicle biology projects Research and understand relevant target/disease biology; design and implement experimentation to validate hypotheses. Prepare presentations and represent the group to cross-functional teams. Train and mentor research associates when appropriate Maintain awareness of current developments in the field through comprehensive reading and analysis of the literature and attendance at appropriate scientific meetings. Understand the competitive landscape and participate in the review and analysis of outside opportunities. Qualifications Minimum Qualifications: Ph.D. or Masters in cell and molecular biology or equivalent subject 5 years of experience with PhD OR 10 with Masters(academic/postdoc or industry) Experience in dermatology or developmental biology or pharmacological evaluation of drugs Extensive experience in mammalian tissue culture with a focus on iPSC culture and differentiation as well as complex cell models to evaluate function. Experience in analysis of big data sets (NGS, -omics, etc.) Translational in vitro functional assays with primary cells and the application of these techniques to pharmacological studies is required. Experience with qPCR, western blot, ELISA, Luminex and immunofluorescence techniques Preferred Skills: Experience with siRNA design/ CRISPR assays and implementation in target validation and functional studies. Experience in drug development setting Other Required Skills: Strong scientific skills with the ability to collaborate with project team members. Must be able to multitask effectively and be adaptable and flexible to meet changing priorities. Motivated team player with a can-do attitude. Must have excellent written and oral communication skills. Committed to the values of integrity, accountability, transparency, scientific rigor and drive. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. This job is eligible to participate in our long-term incentiveprograms Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html