GCLP Research Associate II

GCLP Research Associate II Job ID: req4140 Employee Type: exempt full-time Division: Vaccine, Immunity and Cancer Facility: Frederick: ATRF Location: 8560 Progress Dr, Frederick, MD 21701 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases. Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way. PROGRAM DESCRIPTION The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases. The Vaccine, Immunity, and Cancer Directorate (VICD) at the Frederick National Laboratory has a primary mission to provide scientific leadership and laboratory infrastructure to study immune responses to Human Papillomavirus (HPV) vaccines and other cancer preventive strategies in the context of clinical and pre-clinical studies. More recently, VICD is also leading initiatives on SARS-CoV-2 infection and vaccines. Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public’s interest. KEY ROLES/RESPONSIBILITIES The Research Associate will: Be responsible for sample management Optimize and validate procedures and methodologies for assessment of immune responses to infections and vaccines Plan assays and conduct testing of large number of samples from clinical studies under GCLP Perform serological assays: ELISA, neutralization, multiplex, Luminex Utilize laboratory information management system for lab operation With limited supervision, design and implement protocols, as well as troubleshoot assays and experiments independently Evaluate, analyze and compile data, maintain databases Be responsible for routine QC/QA procedures, ordering supplies, and maintaining equipment and inventories Prepare reports, present data and participate in report and proposal preparation Write and/or modify SOPs as needed Remain current on literature and relevant laboratory techniques Other duties as assigned BASIC QUALIFICATIONS To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below: Possession of Bachelor’s degree in immunology, molecular biology, biology, or other relevant studies from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency In addition to the education requirement, a minimum of five (5) years of relevant laboratory experience Detailed knowledge of vaccines, immunology, and virology Expertise in tissue culture and immunological/virological techniques, including aseptic techniques, cell line maintenance, production of plasmids and virus-like particles, western-blot, ELISA, Luminex assays, flow cytometry, virus neutralization assays and PCR Ability to obtain and maintain a security clearance PREFERRED QUALIFICATIONS Candidates with these desired skills will be given preferential consideration: Master’s degree in relevant studies Experience in standard tissue culture and immunological/virological techniques, including: aseptic techniques, cell line maintenance, production of plasmids and virus-like particles, western-blot, ELISA, Luminex assays, virus neutralization assays and PCR Experience in immune assay (ELISA, multiplex assays) development and validation Experience handling large data sets, statistics, software tools (Word, Excel, PowerPoint) Experience in laboratories operating under GCLP/GMP/GLP/CLIA Experience using and troubleshooting robotics or automation system Experience with electronic documentation systems and LIMS JOB HAZARDS This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations. Commitment to Diversity All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws. 68,600.00 - 117,875.00 The posted pay range for this job is a general guideline and not a guarantee of compensation or salary. Additional factors considered in extending an offer include, but are not limited to, responsibilities of the job, education, experience, knowledge, skills, and abilities as well as internal equity, and alignment with market data. readytowork