Associate Director – ADC Conjugation

Associate Director – ADC ConjugationGaithersburg, MDAs an Associate Director specializing in ADC Conjugation, you will be part of a team of highly skilled and passionate individuals responsible for innovating and generating best-in-class antibody-drug conjugates (ADCs) for the Oncology therapeutic area. This exciting opportunity allows you to lead and contribute to fast-paced, multi-disciplinary drug development efforts.AccountabilitiesTeam Leadership: Manage and mentor a team of conjugation scientists to deliver platform and pipeline-focused drug conjugates for oncology and other therapeutic areas.Workflow Coordination: Coordinate, align, and plan conjugation and analytical workflows within a larger team.Method Development: Develop and optimize novel conjugation methodologies to improve ADC properties.Collaboration: Work collaboratively with a diverse group of scientists across various therapeutic areas, chemistry, and process development to ensure timely progress in research projects and drive technological innovations.Laboratory Maintenance: Lead and coordinate laboratory maintenance, including equipment upkeep and lab safety.Essential Skills/ExperiencePh.D. in Organic Chemistry, Chemical Biology, Biochemistry, or other relevant disciplines with 7+ years of relevant industrial experience or Masters in Organic Chemistry, Chemical Biology, Biochemistry, or other relevant disciplines with 12+ years of relevant industrial experienceADC Design: Demonstrated hands-on experience in the design and generation of antibody-drug conjugates.Analytical Techniques: Working knowledge of characterization using analytical techniques such as Hydrophobic Interaction Chromatography (HIC)-HPLC, Size Exclusion Chromatography (SEC), Liquid Chromatography–Mass Spectrometry (LC-MS), Ion-Exchange (IEX), and Reversed Phase (RP)-HPLC.Protein Purification: Hands-on experience and knowledge of protein purification using HIC, IEX, SEC, and affinity chromatography. Experience with GE AKTA FPLC is preferred.Project Management: Proven ability to work independently, effectively plan and organize work activities, and prioritize task completion to meet project deadlines.Problem-Solving: Demonstrated experience in optimizing/troubleshooting protocols with a problem-solving mindset and maintaining a detailed laboratory notebook.Scientific Innovation: Track record of scientific innovation as evidenced by scientific publications, patents, and oral presentations at conferences.Communication Skills: Excellent written and verbal communication skills and the ability to effectively present complex scientific data to cross-functional teams and senior management.Desirable Skills/ExperienceMass Spectrometry: Strong knowledge in mass spectrometry and other novel analytical techniques for comprehensive assessment of bioconjugates.CRO Coordination: Experience working and coordinating with Contract Research Organizations (CROs)People Management: Experience managing a team of bioconjugation and analytical chemistsAt AstraZeneca, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. Our collaborative environment brings together the best minds from academia and industry to share knowledge, grow together, and build meaningful careers.About Our Gaithersburg Oncology HubOur Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science.So, what’s next?Join us at AstraZeneca and make a meaningful difference for patients around the world!If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.Closing Date: December 16, 2024Competitive remuneration and benefits applyWe offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.Date Posted18-Nov-2024Closing Date15-Dec-2024AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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