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Tempus

Research Scientist

Tempus, Chicago, Illinois, United States, 60290


Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are looking for a highly skilled Research Scientist to join our Biological Modeling team to support Organoid Based Screening. Our CAP accredited facility develops human tumor models for use in a range of studies with our academic and commercial partners to discover next-generation cancer therapies. The ideal candidate will have a strong understanding of molecular gene editing, fluorescent imaging, image analysis, protein detection, and cell culture techniques. Post-doctoral and/or industry experience employing human organoid tissue models in high-throughput formats is preferred.

The successful candidate must be able to work in a fast-paced multidisciplinary environment and will be expected to communicate results both internally and to commercial partners.

What You’ll Do:

Work in a collaborative, interdisciplinary team of scientists employing gene-editing approaches to perturb cellular pathways with the aim of identifying therapeutic targets

Design and execute high-throughput gene-editing, imaging, and protein detection workflows

Culture primary human tissue samples

Work with automated liquid and plate platforms at all stages of development

Execute sequencing studies end-to-end

Develop analysis pipelines to process and visualize large high-throughput data sets

Generate summary reports of screening results and molecular data for customer deliverables

Qualifications:

Ph.D. in oncology, molecular systems biology, or a related field

1+ years of industry or post-doctoral experience

Experience with 3D tissue models preferred, general cell culture experience is a must

Experience generating and assessing next-generation sequencing data is preferred

Proficiency in R and/or Python strongly preferred

Experience with brightfield and fluorescent microscopy

Experience coordinating complex experimental workflows across multidisciplinary teams

Previous experience developing methods for and/or operating automated liquid handlers (Biomek, Echo, etc.)

Benefits:

Competitive salary and benefits package

Collaborative and supportive work environment

Chance to make a real impact on the healthcare industry

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