Principal Research Scientist II, Laboratory Management

Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn . Job Description AbbVie Parenteral Product Development Science & Technology (PDS&T) is a global organization responsible for all CMC activities related to the development and commercialization of AbbVie's parenteral products. Our scope includes AbbVie's diverse pipeline of innovative therapeutic biologics medicines, including monoclonal antibodies, antibody drug conjugates (ADC), and other novelmodalities, and spans from clinical proof of concept through commercial product launch. We are a world-class team of scientists and leaders driving the advancement of industry-leading analytical capabilities and AbbVie's pipeline of innovative medicines. Careers in AbbVie Parenteral PDS&T provide opportunities to work with global and cross-functional teams to develop innovative products and drive exceptional science. The Analytical Development group is responsible for programs that are transitioning from development stage to optimization and commercialization. We lead final method development, optimization, and validation, ensuring all analytical methods are fit for use in commercial QC laboratories. Key deliverables include product control strategies informed by analytical data and method understanding; robust analytical methods suitable for commercial QC labs; comprehensive data packages that drive product and process understanding; stability studies to establish commercial product dating; and approvable marketing application submission content. We are looking for a highly motivated person who can oversee laboratory activities within the Analytical Development team. Key Responsibilities Provide leadership and talent development for a team of scientists responsible for a suite of late-stage biologics products including monoclonal antibodies, antibody drug conjugates, bispecific antibodies, etc. Lead activities associated with analytical characterization of late-stage biologics compounds including assessment of process/formulation development samples, feasibility studies, clinical and commercial in-use, etc. Demonstrate a critical mindset for method troubleshooting, examining data wholistically, and guiding and advising scientists through study execution. Responsible for management of lab activities including established lab standards and best practices, documentation and verification. Independently responsible for project activities within area of expertise while also contributing within the project team to the overall progress of the program. Deliver results in a team-oriented setting and willing to work across scientific disciplines to drive programs through critical milestones. Effectively organize and present scientific plans and data. Author technical documents (e.g., methods, protocols, reports, etc.), scientific publications, presentations, and regulatory documents. Qualifications PhD (8 years), Masters Degree (14 years), or Bachelors Degree (16 years) in scientific discipline (e.g., Analytical Chemistry, Biochemistry, or Biology) with previous laboratory experience. Previous supervisory experience managing teams required. Practical experience with method validation and working in a GMP environment is required including designing studies, authoring protocols and reports, laboratory notebook documentation, etc. Experience with investigations, validation events, out of specification, or out of trend evaluations preferred. Familiarity with analytical Quality by Design (AQbD) preferred. Practical experience and strong knowledge of protein HPLC (e.g., SEC, IEX, HIC), capillary electrophoresis, and other separation techniques as applied to protein analysis is preferred. Solid understanding of protein chemistry and biochemistry, particularly as related to biologics drug development, is preferred. Ability to multitask and work within timelines. Demonstrated scientific writing skills and strong verbal communication skills. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. This job is eligible to participate in our long-term incentiveprograms Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html