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University of California - San Francisco

Staff Research Associate 1/2 - Drug Metabolism and Pharmacokinetics team

University of California - San Francisco, San Francisco, California, United States, 94199


Staff Research Associate 1/2 - Drug Metabolism and Pharmacokinetics Team

IND (Neurodegenerative Dis) Full Time Job Summary At the University of California San Francisco, Institute of Neurogenerative Disease (IND), we are investigating and creating therapies for prion-based neurodegenerative disease, including Alzheimer's, Parkinson's, multiple system atrophy, and chronic traumatic encephalopathy. IND Drug Metabolism and Pharmacokinetics team (DMPK) is searching for a Staff Research Associate (SRA) to: Measure drug concentration in tissue samples using LC-MS. Prepare drug mixtures in liquid and solid formats. Measure drug concentration in prepared drug mixtures. Analyze and audit drug concentration data obtained using LC-MS. Prepare reports based on analyzed and audited drug concentration data. Department Description The Institute for Neurodegenerative Diseases (IND) at UCSF is pursuing a cutting-edge blend of basic science and clinical medicine to provide outstanding care to those suffering from neurodegenerative diseases. Founded in 1999, the IND is committed to creating therapeutics that will halt diseases such as Alzheimer's, Parkinson's, Creutzfeldt-Jakob disease and dementia resulting from traumatic brain injuries. The IND is poised to make serious contributions to this struggle at the frontier of neuroscience and medicine. Required Qualifications SRA I:

BA/BS degree in any STEM field and knowledge of basic techniques or methods required for the position; or an equivalent combination of education and experience. Experience using liquid chromatography-mass spectrometry (LC-MS) to measure drug concentrations in tissue samples, as may have been gained in school or similar training. Proficiency in Excel, Word, Powerpoint, Outlook, Sharepoint, Onedrive, Teams, Zoom. Excellent oral and written communication skills, organizational and record keeping skills. Ability to work as an effective and efficient team member, and to participate in team meetings and planning. Enthusiasm, positive outlook, collegiality and scientific curiosity. SRA II: (including everything above)

1 year of experience with, and knowledge of, basic techniques or methods required for the position; or an equivalent combination of education and experience. Preferred Qualifications 1+ years industry or independent research experience, especially within the field of drug metabolism and pharmacokinetics. Proficiency with pharmacokinetics / pharmacodynamics theory and practice. Proficiency in designing and executing pharmacokinetic experiments and drug formulations. Proficiency in preparing liquid and solid drug formulations. Proficiency with Sciex LC-MS instruments and Sciex LC-MS software e.g. Analyst, DiscoveryQuant, as obtained in school or work experience. Proficiency with BSL-2 sterile technique. Proficiency with Smartsheet, GraphPad Prism, Labguru, Climb, Phoenix WinNonlin. About UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. Equal Employment Opportunity The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Organization: Campus Job Category: Research and Scientific Employee Class: Career Percentage: 100% Location: San Francisco, CA Work Style: Fully On-Site Shift: Days Shift Length: 8 Hours Additional Shift Details: M - F, 8:30 - 5:00

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