Scientist II

Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow abbvie on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok . Job Description Purpose/Primary Job Function The Quantitative Translational ADME Science Department (QTAS) at AbbVie in Worcester, MA is seeking an experienced, independent, creative, and highly motivated scientist to join our non-regulated bioanalytical team. The candidate will conduct preclinical/clinical PK and biomarker assay development and validation as well as sample analysis to support discovery and early development activities of novel therapies in multiple therapeutic areas. The ideal candidate should have hands-on experience in a variety of technologies, including but not limited to ligand binding assays (LBA) on various platforms (ELISA, MSD), quantitative and digital PCR, branched DNA analysis and pre-analytical workflow optimization (sample processing steps), etc. He/she will be a key member of a large molecule PK and biomarker bioanalysis teams supporting all AbbVie therapeutic areas with fit-for-purpose methods to enable discovery and development stage activities. The candidate will identify and optimize assay formats, conduct sample analysis, troubleshoot, and communicate results to key project team members including modelers to advance decision making and candidate drug nominations. Responsibilities Develop, validate, communicate and troubleshoot bioanalytical assays across a variety of platforms (LBA, PCR, etc) and sample matrices (serum and tissues). Lead assay planning and execution of pre-clinical in vivo and exploratory human sample analysis based on bioanalytical protocol and study design. Conduct, and document appropriately compliant biomarker sample testing to support non-clinical and clinical (exploratory) studies. Develop and lead effective partnerships with discovery, preclinical safety, precision medicine, clinical pharmacology, and project team representatives in a highly collaborative and innovative environment to deliver high-impact and quality data in a timely manner. Qualifications Qualifications Education/Experience A minimum of 7 years of working experience with bachelors degree in molecular biology, biochemistry, or other related fields, or 5 years of experience with Masters, or PhD degree in relevant fields. Proficient in LBA (ELISA, MSD, etc.), molecular biology, and genomics related assays, method development, validation, and sample testing workflows to comply with current regulatory standards and best industry practices. Experience in electronic notebooking and data management (LIMS) systems required Excellent communication, time management, and prioritization skills, and proven ability to work effectively as a member of a multidisciplinary team. Demonstrated capacity to work in a fast-paced environment with meticulous attention to detail, and an ability to handle multiple projects, prioritize work, and meet deadlines. Author of relevant publications and reports on bioanalytical assays and drug development fields. Preferred: Experience with automation platforms (Hamilton, Tecan) is a plus Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html