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System One Holdings, LLC

System One Holdings, LLC is hiring: Downstream Manufacturing Scientist in Piscat

System One Holdings, LLC, Piscataway, NJ, United States


Job Title: Downstream Manufacturing Scientist

Location: Greater Piscataway, NJ area

Hours: 1st shift 8am-5pm

Type: Direct Hire

Responsibilities:

  • As a Downstream Manufacturing Scientist you would be responsible for executing purification of mammalian cell-based cultures and producing recombinant proteins for a wide range of mammalian based biosimilars.
  • As the Downstream Manufacturing Scientist, you will be responsible for the purification of 50L to 1000L volumes engineering, clinical and commercial batches in a cGMP environment.
  • You would need to have technical expertise in AKTA purification skids or similar and Tangential Flow Filtration (TFF)
  • You would need to be knowledgeable about initiating batch records, protocols, investigations and other technical documents.


Requirements:

  • Bachelor's or Master's degree in chemical, biological or biochemical sciences
  • 4- 5 years of experience in the biopharmaceutical industry
  • Previous experience working in a GMP and an aseptic manufacturing environment.
  • Experience working with AKTA Process skids or similar
  • Familiarity of single use manufacturing consumables such as bags, tube sets, columns and process manifolds
  • Possess knowledge to execute engineering and clinical batches; familiar with GMP documentation.
  • Basic computer skills, including knowledge of Word, Excel and spread sheet
  • Knowledge of GMP batch manufacturing and packaging documentation; audit and review.
  • Knowledgeable in cleaning verification/validation
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