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X4 Pharmaceuticals

Vice President, US Sales

X4 Pharmaceuticals, Boston, MA


Vice President, US SalesReporting to: Chief Commercial Officer Do you have the passion and commitment to join a team whose mission is to develop treatments that have a clear and profound impact on people with rare diseases? Does it excite you to be a part of a company developing potential new treatments that could dramatically improve the lives of people with limited to no treatment options? Named one of the Top Places to Work by The Boston Globe, X4 is an exceptional place, focused on open communication and collaboration and dedicated to each other, our partners, and the medical community.  With the April 2024 U.S. approval of our first drug XOLREMDI® (mavorixafor), we have made great progress in advancing our patient-centric mission and in evolving the company into a fully integrated pharmaceutical company. But there is so much left to do! We are continuing to explore global opportunities for mavorixafor in its first indication, while also advancing mavorixafor for people with chronic neutropenia through an ongoing pivotal, global Phase 3 clinical trial. In addition, our research team in Vienna, Austria is focusing on new drug discovery and examining the genetic causes of chronic neutropenic disorders. We recognize that developing innovative, new medicines is challenging, but we embrace this challenge to truly make progress for patients each day. If you feel you would be a good fit for X4, we invite you to share with us your aspirations and career goals. At X4 you will find… A team that values grit and passion of innovative science.The opportunity to leverage your knowledge of US Sales to support our innovative science and allow you to have a major impact on our mission to support our patients.  A collegial environment with a team-based approach, where our mission drives our values, behaviors, and creativity.  X4 is seeking a Vice President of Sales to be a member of the commercial leadership team as they work together to maximize the US launch of XOLREMDI® in WHIM syndrome. This person will be responsible for attracting, retaining, and leading the sales organization including the development of the sales deployment strategy, and the planning and execution of tactics to optimize HCP targeting, patient identification, and the adoption of XOLREMDI®. The long-term goal will be to continue growth and optimization of the Sales function into an  organization supporting multiple indications and/or products. This leadership role is responsible for raising disease awareness, supporting patient finding and executing compliant product promotion to all external customers, leading agency and vendor relationships as required, establishing and developing KOL relationships, and leading cross functional collaboration internally and externally. The VP will contribute to building a culture of continuous learning and improvement while developing capabilities and talent across the sales team.  They will inspire the team to educate customers on the importance of early diagnosis of WHIM syndrome and support access to medicines for our patients. The VP will align and contribute to the company’s mission by championing a collaborative, cross-functional business model and approach.Accountabilities and Responsibilities:The Vice President, US Sales will work closely with a breadth of the company’s functional groups, including but not limited to, Commercial Operations, Marketing, Market Access, Finance, Regulatory Affairs, Legal/Compliance, Medical Affairs, as well as business partners to ensure organizational alignment with the commercialization strategy. In this leadership position, this executive will: Demonstrate company values on a consistent basis.Help establish commercial and corporate goals, and advocate for the required budget and resources from the executive team. Be held accountable for achieving annual US demand objectives. Train, coach, develop, motivate the Sales team. Lead, refine and execute business plans by geography, sales force sizing and deployment, customer targeting, and prioritized field direction.Partner with Commercial Operations and Marketing on lead optimization, and support field reporting to enable closing the loop to validate/invalidate leads.Contribute to the brand strategy, sales tool development and targeting strategies by championing customer insights, institutional and HCP profiling, and CRM data capture by the Sales team and collaborating with/communicating insights to Commercial Operations and Marketing. Utilize data and insights to continuously enhance operational effectiveness, enabling the Sales team to make smarter decisions about which customers to target, the most effective tools and messages to use in various scenarios, and the appropriate cross-functional colleagues to engage.Encourage and support feedback loop and collaboration with Marketing through support of the Field Advisory Board.Assist with developing and conducting key performance metrics, performance evaluations and incentive compensation planning to drive desired performance and behaviors.Build capabilities and knowledge in the field Sales team through ongoing education and training to drive success and position the Company as a leader in our space.Create compelling and robust development and succession plans for all key positions within the Sales function. Drive innovation in strategy and tactics to build disease and brand awareness, excitement, intent to diagnose patients, and prescribe XOLREMDI®.Identify and align on market research needs, and plans with Commercial Operations, and help translate insights into tactical plans, sales execution, and forecasting assumptions. Work collaboratively with key thought leaders, academic institutions, professional and patient advocacy groups to support disease awareness, diagnosis, commercial success in the US. Provide input on payer/pricing strategies, distribution channels and improvements in the patient support services Hub.Partner with prescribing HCP’s staff, patient support services Hub, and Market Access team to ensure patients convert prescriptions to gain reimbursement and adhere to treatment.Monitor and manage the Sales function’s budgets and expense forecasts, while evaluating cost effectiveness and ROI of activities and results. Acts, and is accountable for others in his/her team to act, in compliance with all laws, regulations and policies.Requirements:  Proven Experience, Skills, and Education:A proven track record of successfully launching therapeutic products in the rare disease space, preferably in immunology and/or hematology. A strong sales and operations background and recent launch experience within a start-up company is preferred.Successfully led integrated commercial organizations and have demonstrated the ability to attract, retain and develop top tier talent. Deep knowledge and experience in the US market of biopharma commercialization is required. Experience and prior success leveraging data and advanced analytics to optimize field targeting and engagement.Superior leadership, strategic and analytical capabilities, aligning teams and partnering productively with peer functions (Commercial Operations, Market Access, Medical, Finance, etc.) with an established vision and rigor that inspires action and execution of strategy. Sophisticated, executive-level communication skills to play a key market-facing role alongside the CCO. An attraction to the opportunity to be part of an effort, and persuade others, that has the potential to fundamentally change the current treatment options with a significant unmet need. An experienced and dynamic commercial leader and strategist who will thrive within a growing, collaborative, entrepreneurial biotech company. Hands-on approach, having a sense of urgency, mature judgment, and conduct business and personal actions reflective of the company’s core values. Capable of quickly gaining the trust and credibility of sales team and other employees and external stakeholders, based on integrity, competency, and the honoring of commitments. Familiar with recruiting and building teams around shared goals. A well-established commercial network is strongly preferred. Strong verbal and written communication skills along with comfort with public presentations. MA/MS or higher education.We encourage you to learn more about X4 Pharmaceuticals. Click on the links below!About UsPipelineX4 Pharmaceuticals is an Equal Opportunity, and Affirmative Action Employer committed to a culturally diverse workforce.  All qualified candidates will receive consideration without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender identity or expression, sexual orientation, disability, veteran status, violence victim status or any other characteristic protected by law.#LI-Hybrid