Gilead Sciences, Inc.
Senior Associate Scientist, Oncology Research
Gilead Sciences, Inc., Foster City, California, United States, 94420
Senior Associate Scientist, Oncology Research
Gilead Sciences (Foster City, CA) is seeking a talented and highly motivated scientist to join our oncology research group. Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic. The successful candidate is expected to contribute to the discovery, research, and development of novel therapeutic agents to address unmet medical needs of cancer patients. S/he will have opportunities for career growth through acquisition of new skills, experiences, and professional relationships in a fast-paced and resource-rich environment. Key Responsibilities Independently plan, execute, analyze, troubleshoot, and interpret
in vitro
and
ex vivo
experiments that support non-routine research activities and projects goals. Proactively evaluate new technologies and develop new assays to accelerate early-stage discovery activities and/or enhance our understanding of disease mechanisms. Support multiple projects simultaneously and work cross-functionally with colleagues in the oncology, chemistry, protein engineering, pathobiology, DMPK, biomarker and clinical groups. Present research findings and recommendations to senior staff and contribute to preparation of research reports, manuscripts, INDs, and patent filings. Provide coaching and training to junior and/or less experienced colleagues in solving technical and scientific problems. Education Master's degree and 8+ years of experience or Bachelor's degree and 10+ years of experience in cell biology, molecular biology, or biochemistry in biotechnology or pharmaceutical industry. Required experience and skills Extensive experience in cancer cell biology, target identification/validation in oncology or immuno-oncology. Experience working with small molecules. Extensive experience in general molecular and cell biology methods including primary human and mouse cell culture and basic flow cytometry. High proficiency in techniques evaluating cell signaling (e.g. western blot, ELISA, MSD, immunofluorescence, reporter-based assays) and proliferation/survival using small-molecules and biologics. Proficiency in methods evaluating gene expression (e.g. RT-qPCR, Nanostring and others). Experience with methods to perturb gene function (e.g. RNAi, CRISPR, overexpression) and to deliver constructs (e.g. transfection, electroporation, lentiviral transduction). Experience with quantitative cellular assays. Attention to detail with excellent organizational and record keeping skills. Excellent communication and interpersonal skills. Preferred skills Expertise in cell cycle analysis and high content imaging. A strong record of achievements, contributions to drug discovery programs and publications. The salary range for this position is: $133,280.00 - $172,480.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws.
#J-18808-Ljbffr
Gilead Sciences (Foster City, CA) is seeking a talented and highly motivated scientist to join our oncology research group. Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic. The successful candidate is expected to contribute to the discovery, research, and development of novel therapeutic agents to address unmet medical needs of cancer patients. S/he will have opportunities for career growth through acquisition of new skills, experiences, and professional relationships in a fast-paced and resource-rich environment. Key Responsibilities Independently plan, execute, analyze, troubleshoot, and interpret
in vitro
and
ex vivo
experiments that support non-routine research activities and projects goals. Proactively evaluate new technologies and develop new assays to accelerate early-stage discovery activities and/or enhance our understanding of disease mechanisms. Support multiple projects simultaneously and work cross-functionally with colleagues in the oncology, chemistry, protein engineering, pathobiology, DMPK, biomarker and clinical groups. Present research findings and recommendations to senior staff and contribute to preparation of research reports, manuscripts, INDs, and patent filings. Provide coaching and training to junior and/or less experienced colleagues in solving technical and scientific problems. Education Master's degree and 8+ years of experience or Bachelor's degree and 10+ years of experience in cell biology, molecular biology, or biochemistry in biotechnology or pharmaceutical industry. Required experience and skills Extensive experience in cancer cell biology, target identification/validation in oncology or immuno-oncology. Experience working with small molecules. Extensive experience in general molecular and cell biology methods including primary human and mouse cell culture and basic flow cytometry. High proficiency in techniques evaluating cell signaling (e.g. western blot, ELISA, MSD, immunofluorescence, reporter-based assays) and proliferation/survival using small-molecules and biologics. Proficiency in methods evaluating gene expression (e.g. RT-qPCR, Nanostring and others). Experience with methods to perturb gene function (e.g. RNAi, CRISPR, overexpression) and to deliver constructs (e.g. transfection, electroporation, lentiviral transduction). Experience with quantitative cellular assays. Attention to detail with excellent organizational and record keeping skills. Excellent communication and interpersonal skills. Preferred skills Expertise in cell cycle analysis and high content imaging. A strong record of achievements, contributions to drug discovery programs and publications. The salary range for this position is: $133,280.00 - $172,480.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws.
#J-18808-Ljbffr