Scientist/Sr. Scientist, Preclinical Research and Development

Cullinan Therapeutics, Inc. (Nasdaq: CGEM) is a biopharmaceutical company dedicated to creating new standards of care for patients. We have strategically built a diversified portfolio of clinical-stage assets that inhibit key drivers of disease or harness the immune system to eliminate diseased cells in both oncology and autoimmune disease. Our portfolio encompasses a wide range of modalities, each with the potential to be best and/or first in class. Anchored in a deep understanding of oncology, immunology, and translational medicine, we create differentiated ideas, identify the most appropriate targets, and select the optimal modality to develop transformative therapeutics across a wide variety of cancer and autoimmune indications. We push conventional boundaries from candidate selection to differentiated therapeutic, applying rigorous go/no go criteria at each stage of development to fast-track only the most promising molecules to the clinic and, ultimately, commercialization. With deep scientific expertise, our teams exercise creativity and urgency to deliver on our promise to bring new therapeutic solutions to patients. Summary: The position will be responsible for overseeing and/or supporting early stage drug development projects in the Cullinan pipeline. All research activities will be conducted in a virtual manner, with the position overseeing projects through a global network of contract research organizations and research collaborations. Oversight may span early discovery to development candidate selection and IND-enabling studies. The primary goal of the position will be to direct research projects and work collaboratively to establish the next generation of novel assets for Cullinan’s pipeline. Position Responsibilities:

Lead and oversee contract research organizations in discovery efforts, including but not limited to construct generation, in vitro characterization, in vivo models and mechanistic studies. Design and execute program strategy and research plans, including assay design, technical workflow management and resource allocation. Develop budget forecasts for drug development programs, including review of active contracts and long-range planning. Day-to-day oversight of external research efforts, including but not limited to identification of vendors, review/approval of work orders, protocol design, assay optimization, troubleshooting data review, data analysis using biological and statistical software (Prism, Excel, other), and data management/organization. Deliver impactful presentations to share program updates and data with colleagues including senior leadership. Oversee logistical management of Cullinan samples, including shipment/storage of materials and maintaining a running material inventory. Lead internal technical discussions on preclinical programs. Develop innovative strategies to move existing programs forward. Lead internal innovation projects and generate ideas for new pipeline programs. Routinely review relevant scientific literature and competitive landscape; attend scientific conferences. Author/review regulatory submissions documents related to nonclinical IND-enabling studies. Participate in diligence activities to support the evaluation of potential new assets for addition to Cullinan portfolio. Candidate Requirements:

1-3 years of industry experience. PhD in cancer immunotherapy, immunology, cancer biology, biological engineering, biochemistry, or a related field. Experience in cancer and/or immunology research, preferably with experience in immuno-oncology, autoimmunity and/or protein engineering. Experience evaluating drug asset value propositions, either in venture capital or in the biotech industry, is preferred. Innovative thinker. Strong attention to detail. Highly collaborative, with an interest in working within and across teams. Excellent verbal and written communication skills to serve as liaison between Cullinan and contract research organizations and other outward-facing partners. Ability to excel in a fast-paced work environment with focus on multiple programs in parallel. Cullinan Therapeutics is proud to be an Equal Opportunity Employer. We are committed to creating an inclusive and diverse environment for all employees and applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.

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