Takeda Pharmaceutical
Research (Scientific) Associate Director, Computational Chemistry
Takeda Pharmaceutical, Boston, Massachusetts, United States,
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the information I provide in my application will be processed in line with
Takeda’s
Privacy Notice
and
Terms of Use .
I further attest that all information I submit in my employment application
is
true to the best of my knowledge.
Job Description Job Posting Description
At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide. Objective / Purpose: As a Computational Chemistry Leader, you will work as part of a multi-disciplinary team of Medicinal Chemists, Computational Chemists, Data Scientist, Structural Biologists, Pharmacologists and Biologists to provide Computational expertise to advance drug discovery projects
Contribute to drug discovery efforts across various modalities including small molecules, bifunctional degraders, peptides, RNA/oligonucleotides, and biologics
Implement and execute innovative computational methodologies and tools such as AI approaches to support drug discovery efforts
Accountabilities: Demonstrate expert understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment
Identify, develop, validate, and implement innovative computational approaches that improve research productivity and success
Provide crucial technical knowledge and input to project teams to drive decision-making in drug discovery projects
Build and develop a strong team of Computational Chemists to high productivity levels
Demonstrate leadership and enterprise thinking in managing multi-disciplinary team
DIMENSIONS AND ASPECTS: Expertise in a variety of computational tools and methodologies including docking, virtual screening, molecular dynamics, free energy perturbation, homology modeling, quantum mechanics, pharmacophore elucidation, data mining, machine learning, cheminformatics, clustering, similarity & diversity analysis
Significant Industry experience contributing as Computational Chemist on drug discovery projects
Strong Impact in progressing Discovery Projects from Hits to Clinical Leads
Extensive knowledge & experience in using a variety of tools for Hit ID
Provide project teams with computational strategies to inform, influence, and prioritize compound designs for potency/selectivity and improve ADME/Tox endpoints
Ability to effectively integrate emerging generative chemistry methods and other modern machine learning and artificial intelligence (AI) applications in small molecule drug discovery
Proficiency with state-of-the-art Computational Chemistry software
Network with renowned researchers in computational chemistry/AI
EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS: PhD degree in a relevant scientific discipline
6+ years of Industry (pharma/biotech) drug discovery experience required
Takeda Compensation and Benefits Summary
We understand compensation is
an important factor
as you consider the next step in your career. We are committed to
equitable
pay for all employees, and we strive to be more transparent with our pay practices.
For Location: Boston, MA U.S. Base Salary Range: 149,100.00 - 234,300.00 The estimated salary range reflects
an anticipated
range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education
attained
, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
?
The actual base salary offered will be
in accordance with
state or local minimum wage requirements for the job location.
U.S. based
e
mployee
s
may be eligible for
s
hort
-
t
erm and/
or
l
ong-
t
erm
incentive
s
.
U.S.
based employees
may be
eligible to
participate
in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and
well-being
benefits, among others. U.S.
based employees are also eligible to receive, per calendar year, up to
80 hours
of sick time, and new hires are eligible to
accrue
up to
120 hours of paid vacation.
EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
Boston, MA Worker Type
Employee Worker Sub-Type
Regular Time Type
Full time Job Exempt Yes
the information I provide in my application will be processed in line with
Takeda’s
Privacy Notice
and
Terms of Use .
I further attest that all information I submit in my employment application
is
true to the best of my knowledge.
Job Description Job Posting Description
At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide. Objective / Purpose: As a Computational Chemistry Leader, you will work as part of a multi-disciplinary team of Medicinal Chemists, Computational Chemists, Data Scientist, Structural Biologists, Pharmacologists and Biologists to provide Computational expertise to advance drug discovery projects
Contribute to drug discovery efforts across various modalities including small molecules, bifunctional degraders, peptides, RNA/oligonucleotides, and biologics
Implement and execute innovative computational methodologies and tools such as AI approaches to support drug discovery efforts
Accountabilities: Demonstrate expert understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment
Identify, develop, validate, and implement innovative computational approaches that improve research productivity and success
Provide crucial technical knowledge and input to project teams to drive decision-making in drug discovery projects
Build and develop a strong team of Computational Chemists to high productivity levels
Demonstrate leadership and enterprise thinking in managing multi-disciplinary team
DIMENSIONS AND ASPECTS: Expertise in a variety of computational tools and methodologies including docking, virtual screening, molecular dynamics, free energy perturbation, homology modeling, quantum mechanics, pharmacophore elucidation, data mining, machine learning, cheminformatics, clustering, similarity & diversity analysis
Significant Industry experience contributing as Computational Chemist on drug discovery projects
Strong Impact in progressing Discovery Projects from Hits to Clinical Leads
Extensive knowledge & experience in using a variety of tools for Hit ID
Provide project teams with computational strategies to inform, influence, and prioritize compound designs for potency/selectivity and improve ADME/Tox endpoints
Ability to effectively integrate emerging generative chemistry methods and other modern machine learning and artificial intelligence (AI) applications in small molecule drug discovery
Proficiency with state-of-the-art Computational Chemistry software
Network with renowned researchers in computational chemistry/AI
EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS: PhD degree in a relevant scientific discipline
6+ years of Industry (pharma/biotech) drug discovery experience required
Takeda Compensation and Benefits Summary
We understand compensation is
an important factor
as you consider the next step in your career. We are committed to
equitable
pay for all employees, and we strive to be more transparent with our pay practices.
For Location: Boston, MA U.S. Base Salary Range: 149,100.00 - 234,300.00 The estimated salary range reflects
an anticipated
range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education
attained
, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
?
The actual base salary offered will be
in accordance with
state or local minimum wage requirements for the job location.
U.S. based
e
mployee
s
may be eligible for
s
hort
-
t
erm and/
or
l
ong-
t
erm
incentive
s
.
U.S.
based employees
may be
eligible to
participate
in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and
well-being
benefits, among others. U.S.
based employees are also eligible to receive, per calendar year, up to
80 hours
of sick time, and new hires are eligible to
accrue
up to
120 hours of paid vacation.
EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
Boston, MA Worker Type
Employee Worker Sub-Type
Regular Time Type
Full time Job Exempt Yes