ZipRecruiter
Sr. Scientist
ZipRecruiter, San Mateo, California, United States, 94409
R&D Partners is seeking to hire a Scientist/Sr. Scientist
in
San Carlos, CA .
The title and compensation of the candidate will be adapted according to their credentials. For the next 1-2 years, the candidate’s primary responsibility will be to contribute to process characterization efforts for the company’s pneumococcal conjugate vaccine program. After that, the candidate will work on conjugation process development for pipeline programs. Specifically, this will include preparation, purification, and analytical characterization of chemically modified polysaccharides and polysaccharide-protein conjugates. The ideal candidate will have significant laboratory experience and an excellent understanding of analytical chemistry principles. The successful candidate will be expected to design, execute, and troubleshoot experiments with minimal guidance.
Your main responsibilities as a Scientist/Sr. Scientist, Conjugations:
Optimize and troubleshoot multi-step syntheses of protein-polysaccharide conjugates.
Purify polysaccharides and conjugates using a variety of methods including dialysis, size-exclusion chromatography, and tangential flow filtration (TFF).
Analyze polysaccharides and conjugates with a variety of analytical methods. Develop new laboratory workflows and analyses beyond established procedures when appropriate.
Advise team members on experimental design, interpretation of results, and troubleshooting.
Model and train team members on best practices for adherence to protocols and data management.
Serve as a subject matter expert during tech transfer of conjugation processes to contract manufacturing organizations.
Maintain highly organized records to enable optimization and assessment of reproducibility.
Attend team meetings ready to provide updates on conjugation development progress.
What we are looking for in a Scientist/Sr. Scientist:
PhD in chemistry, biochemistry, or related field with 2-5+ years of industry experience.
Strong biochemistry and organic chemistry knowledge base underpinning several years’ experience preparing bioconjugates.
Proficiency with small- and large-scale techniques for purification of bioconjugates, including tangential flow filtration.
Proficiency in a variety of techniques for bioconjugate analysis such as colorimetric assays, HPLC, and SEC-MALS.
Sufficient knowledge of analytical principles to develop fit-for-purpose analytical methods as needed and provide cross-functional feedback on draft analytical methods.
Experience with Design of Experiments is desirable.
Experience with chemical modification of polysaccharides is desirable.
Pay Scale:
$152,000 - $170,000 annually
R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.
R&D Partners is an equal-opportunity employer.
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in
San Carlos, CA .
The title and compensation of the candidate will be adapted according to their credentials. For the next 1-2 years, the candidate’s primary responsibility will be to contribute to process characterization efforts for the company’s pneumococcal conjugate vaccine program. After that, the candidate will work on conjugation process development for pipeline programs. Specifically, this will include preparation, purification, and analytical characterization of chemically modified polysaccharides and polysaccharide-protein conjugates. The ideal candidate will have significant laboratory experience and an excellent understanding of analytical chemistry principles. The successful candidate will be expected to design, execute, and troubleshoot experiments with minimal guidance.
Your main responsibilities as a Scientist/Sr. Scientist, Conjugations:
Optimize and troubleshoot multi-step syntheses of protein-polysaccharide conjugates.
Purify polysaccharides and conjugates using a variety of methods including dialysis, size-exclusion chromatography, and tangential flow filtration (TFF).
Analyze polysaccharides and conjugates with a variety of analytical methods. Develop new laboratory workflows and analyses beyond established procedures when appropriate.
Advise team members on experimental design, interpretation of results, and troubleshooting.
Model and train team members on best practices for adherence to protocols and data management.
Serve as a subject matter expert during tech transfer of conjugation processes to contract manufacturing organizations.
Maintain highly organized records to enable optimization and assessment of reproducibility.
Attend team meetings ready to provide updates on conjugation development progress.
What we are looking for in a Scientist/Sr. Scientist:
PhD in chemistry, biochemistry, or related field with 2-5+ years of industry experience.
Strong biochemistry and organic chemistry knowledge base underpinning several years’ experience preparing bioconjugates.
Proficiency with small- and large-scale techniques for purification of bioconjugates, including tangential flow filtration.
Proficiency in a variety of techniques for bioconjugate analysis such as colorimetric assays, HPLC, and SEC-MALS.
Sufficient knowledge of analytical principles to develop fit-for-purpose analytical methods as needed and provide cross-functional feedback on draft analytical methods.
Experience with Design of Experiments is desirable.
Experience with chemical modification of polysaccharides is desirable.
Pay Scale:
$152,000 - $170,000 annually
R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.
R&D Partners is an equal-opportunity employer.
#J-18808-Ljbffr