Senior Manager, Companion Diagnostics

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.The Opportunity:RevMed is offering a unique opportunity for a highly motivated individual to join our Companion Diagnostics team as an Sr. Manager, Companion Diagnostics within the Translational Medicine team, which supports CDx development across RevMed portfolio. We are seeking a creative and highly motivated leader to implement global diagnostic strategies to enable and support the global development and commercialization of medically differentiated therapies. The successful candidate will have the opportunity to work in a fast-paced, highly collaborative environment and will be a key member of multidisciplinary development project teams.Required Skills, Experience and Education:Lead the development and implementation of diagnostic strategies for individual studies and/or molecule program.Direct the development, outsourcing and validation of clinically applicable in vitro diagnostic assays through the development lifecycle of molecules, including design, implement and oversee diagnostic testing strategy and timely communication with key internal and external stakeholders.Provide expertise to development project teams to ensure access to state-of-the-art approaches on appropriate diagnostic technologies, evaluating their scientific basis and clinical applicability, the validation status and any technical or statistical issues related to the proposed companion diagnostic assay.Oversee implementation of clinical trial assays at CRO laboratories for centralized testing. Monitors of all scope or changes in study are timely implemented, including the development of the work order, costs and agreements.Individuals may lead joint development teams between RevMed and Dx partners to ensure alignment of overarching development and commercialization strategy, successful fit for purpose CDx development and that co-development timelines are met.Serve as subject matter expert in state-of-the-art biomarker testing technologies (tissue and ctDNA NGS, PCR, immunohistochemistry, FISH, , etc.)Serve as subject matter expert and support the interactions with global health authorities regarding companion diagnostics development and submissions.Preferred Skills:Highly experienced biomarker or diagnostics professional (MS and/or PhD) with a minimum of 5-7 years of relevant industry experience with expertise in oncology biomarker and/or companion diagnostic developmentHigh level of initiative and ability to work independently with business awareness, hands on experience in IVD development processes and global in vitro diagnostic regulatory aspects related to companion diagnostic developmentExperience with biomarker application in clinical trials and awareness of the challenges of implementing diagnostic technologies in the clinical settingExcellent leadership skills including motivation and influencing without authority.Highly collaborative team player who fosters open communication and facilitates mutual understanding and cooperation between all stakeholders with excellent communication, analytical and organizational skills.Cross-functional experience in commercial and or medical aspects of companion diagnostics is a plus.The base salary range for this full-time position is $158,000 to $198,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.#LI-Hybrid #LI-SH1