Disc Medicine
Senior Statistical Programmer
Disc Medicine, Boston, Massachusetts, us, 02298
Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.
COMPANY OVERVIEW:
Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.
POSITION OVERVIEW
:
Disc Medicine is seeking a Senior Statistical Programmer to join our team at a pivotal moment in our company's growth. In this role, you will play a critical part in supporting our clinical programs by generating and analyzing clinical trial data, collaborating cross-functionally, and contributing to the development of transformative therapies for hematologic diseases.
This position offers a unique opportunity to work across early-phase, Phase 2, and pivotal studies, leading statistical programming efforts that directly inform regulatory submissions and clinical development strategies. Reporting to the Senior Director, Clinical Scientist, the successful candidate will engage with internal teams and external vendors to deliver high-quality analyses and integrate translational research insights into clinical programs.
RESPONSIBILITIES:
Conduct programmatic analyses across clinical programs, including integrated safety reports and ad hoc analyses. Lead internal programming efforts for early-stage clinical trials and analyze new and legacy clinical data sets. Collaborate with vendors on the generation and review of SDTM and ADaM datasets and outputs. Work closely with clinical and research teams to integrate translational research into development and clinical strategies. Partner with data management vendors to identify and resolve data issues. Provide input on CRF design, protocol development, and statistical analysis plans. Lead data analysis efforts for regulatory submissions. Review statistical content in clinical and regulatory documents, including protocols, INDs, CTAs, investigator brochures, CSRs, and annual reports. Strategically support study execution while contributing to broader clinical development goals. Guide internal and external teams, vendors, and consultants on efficacy and safety data evaluation. REQUIREMENTS:
Master's or PhD in Biostatistics, Statistics, or a related field. 6+ years of experience with a Master's degree or PhD with 3+ years of experience required. Expertise in statistical programming within clinical or translational research, with strong proficiency in SAS. Broad expertise in clinical data analysis and interpretation, including integrated analyses and safety reporting. Familiarity with principles of clinical research methodology, biostatistics, and regulatory requirements. Strong strategic thinking with a consistent focus on execution. Proven ability to collaborate across functions and organizations. Attention to detail with a commitment to scientific rigor. Excellent communication skills and the ability to engage with key opinion leaders and clinical centers. Strong business acumen: including in-depth knowledge of the multidisciplinary functions involved in a company's drug development process, e.g., clinical operations, biostatistics, regulatory, commercial operations, etc. and can proactively integrate multiple perspectives into the clinical development process for best end-results. Commitment to fostering an inclusive and diverse workplace culture.
Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.
Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit a cover letter and resume to be considered for current and future opportunities.
COMPANY OVERVIEW:
Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.
POSITION OVERVIEW
:
Disc Medicine is seeking a Senior Statistical Programmer to join our team at a pivotal moment in our company's growth. In this role, you will play a critical part in supporting our clinical programs by generating and analyzing clinical trial data, collaborating cross-functionally, and contributing to the development of transformative therapies for hematologic diseases.
This position offers a unique opportunity to work across early-phase, Phase 2, and pivotal studies, leading statistical programming efforts that directly inform regulatory submissions and clinical development strategies. Reporting to the Senior Director, Clinical Scientist, the successful candidate will engage with internal teams and external vendors to deliver high-quality analyses and integrate translational research insights into clinical programs.
RESPONSIBILITIES:
Conduct programmatic analyses across clinical programs, including integrated safety reports and ad hoc analyses. Lead internal programming efforts for early-stage clinical trials and analyze new and legacy clinical data sets. Collaborate with vendors on the generation and review of SDTM and ADaM datasets and outputs. Work closely with clinical and research teams to integrate translational research into development and clinical strategies. Partner with data management vendors to identify and resolve data issues. Provide input on CRF design, protocol development, and statistical analysis plans. Lead data analysis efforts for regulatory submissions. Review statistical content in clinical and regulatory documents, including protocols, INDs, CTAs, investigator brochures, CSRs, and annual reports. Strategically support study execution while contributing to broader clinical development goals. Guide internal and external teams, vendors, and consultants on efficacy and safety data evaluation. REQUIREMENTS:
Master's or PhD in Biostatistics, Statistics, or a related field. 6+ years of experience with a Master's degree or PhD with 3+ years of experience required. Expertise in statistical programming within clinical or translational research, with strong proficiency in SAS. Broad expertise in clinical data analysis and interpretation, including integrated analyses and safety reporting. Familiarity with principles of clinical research methodology, biostatistics, and regulatory requirements. Strong strategic thinking with a consistent focus on execution. Proven ability to collaborate across functions and organizations. Attention to detail with a commitment to scientific rigor. Excellent communication skills and the ability to engage with key opinion leaders and clinical centers. Strong business acumen: including in-depth knowledge of the multidisciplinary functions involved in a company's drug development process, e.g., clinical operations, biostatistics, regulatory, commercial operations, etc. and can proactively integrate multiple perspectives into the clinical development process for best end-results. Commitment to fostering an inclusive and diverse workplace culture.
Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.
Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit a cover letter and resume to be considered for current and future opportunities.