Verve Therapeutics
Scientist, Research Statistics
Verve Therapeutics, Boston, Massachusetts, us, 02298
The Company
Verve Therapeutics is a biotechnology company created with a singular focus: to protect the world from heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, the company aims to develop transformative, once-and-done therapies for coronary heart disease. Verve’s gene editing medicines are designed to safely edit the genome of adults and mimic naturally occurring gene variants to permanently lower LDL cholesterol and triglyceride levels. The company is advancing a pipeline of precision genetic medicines, led by VERVE-101, which is being developed initially for heterozygous familial hypercholesterolemia, a potentially fatal genetic heart disease. In 2023, Verve was named a Top Place to Work by The Boston Globe for the third consecutive year. Verve is headquartered in Boston, Massachusetts.
The Position
Verve is seeking a highly motivated and talented Scientist with experience in implementation, evaluation and application of statistical methods for the analysis of next generation sequencing (NGS) data to join our Computational Biology team. This position will focus on development, benchmarking and integration of appropriate statistical methods into high throughput computational analyses for advancing Verve’s pipeline of precision genetic medicines. The ideal candidate will have expertise with broad range of statistical methodologies suitable for modeling NGS data, characterization of their performance and associated tradeoffs and their integration into computational workflows, including delivery of the key analyses results for the regulatory filings at Verve. If you are passionate about having an impact on improving the lives of patients with cardiovascular disease by means of cutting-edge gene-editing platforms as part of highly collaborative, fast-paced, multidisciplinary dynamic team, we would love to hear from you!
Job ResponsibilitiesEvaluation of statistical tools performance characteristics and guiding their deployment in the context of production-scale pipelines for the analysis of diverse sequencing dataProviding guidance for the choice of statistical methods employed for analysis of the data from newly established and existing assays across the organizationExecution of computational and statistical analyses of high volume NGS data, including development and validation of statistical models, and promoting reliability and reproducibility of the analysis resultsCollaboration with cross-functional teams contributing to experiment design, selecting statistical methodology, prioritizing program objectivesEffective communication of the analysis results to key technical and non-technical stakeholders through reports, presentations and documentationContribution of data visualization and technical writing to scientific reports, manuscripts and regulatory filings supporting Verve’s therapeutic pipelineOther duties as assignedQualificationsPh.D. in biostatistics, applied math/stats or related discipline with 2+ years of relevant industry experience,or M.S. in biostatistics, applied math/stats or related discipline with 7+ years of experienceor B.S. in biostatistics, applied math/stats or related discipline with 9+ years of experienceSolid expertise in common methodologies and frameworks (Python/R preferred) for the statistical analysis of NGS data (required)Extensive experience in applying statistical tools to draw robust conclusions from complex datasets (required)Fluency in tools, frameworks, and methodologies instrumental for reproducible researchExperience with best practices in software development (version control, documentation, unit/integration testing)Experience with high-performance cloud computing environments and computational workflowsStrong analytical and problem-solving abilities, excellent communication and interpersonal skillsCollaborative and detail-oriented approach to efficient performance across multiple teams and projects in a highly matrixed environmentEEO StatementVerve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
Recruitment & Staffing AgenciesVerve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.#J-18808-Ljbffr
Verve Therapeutics is a biotechnology company created with a singular focus: to protect the world from heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, the company aims to develop transformative, once-and-done therapies for coronary heart disease. Verve’s gene editing medicines are designed to safely edit the genome of adults and mimic naturally occurring gene variants to permanently lower LDL cholesterol and triglyceride levels. The company is advancing a pipeline of precision genetic medicines, led by VERVE-101, which is being developed initially for heterozygous familial hypercholesterolemia, a potentially fatal genetic heart disease. In 2023, Verve was named a Top Place to Work by The Boston Globe for the third consecutive year. Verve is headquartered in Boston, Massachusetts.
The Position
Verve is seeking a highly motivated and talented Scientist with experience in implementation, evaluation and application of statistical methods for the analysis of next generation sequencing (NGS) data to join our Computational Biology team. This position will focus on development, benchmarking and integration of appropriate statistical methods into high throughput computational analyses for advancing Verve’s pipeline of precision genetic medicines. The ideal candidate will have expertise with broad range of statistical methodologies suitable for modeling NGS data, characterization of their performance and associated tradeoffs and their integration into computational workflows, including delivery of the key analyses results for the regulatory filings at Verve. If you are passionate about having an impact on improving the lives of patients with cardiovascular disease by means of cutting-edge gene-editing platforms as part of highly collaborative, fast-paced, multidisciplinary dynamic team, we would love to hear from you!
Job ResponsibilitiesEvaluation of statistical tools performance characteristics and guiding their deployment in the context of production-scale pipelines for the analysis of diverse sequencing dataProviding guidance for the choice of statistical methods employed for analysis of the data from newly established and existing assays across the organizationExecution of computational and statistical analyses of high volume NGS data, including development and validation of statistical models, and promoting reliability and reproducibility of the analysis resultsCollaboration with cross-functional teams contributing to experiment design, selecting statistical methodology, prioritizing program objectivesEffective communication of the analysis results to key technical and non-technical stakeholders through reports, presentations and documentationContribution of data visualization and technical writing to scientific reports, manuscripts and regulatory filings supporting Verve’s therapeutic pipelineOther duties as assignedQualificationsPh.D. in biostatistics, applied math/stats or related discipline with 2+ years of relevant industry experience,or M.S. in biostatistics, applied math/stats or related discipline with 7+ years of experienceor B.S. in biostatistics, applied math/stats or related discipline with 9+ years of experienceSolid expertise in common methodologies and frameworks (Python/R preferred) for the statistical analysis of NGS data (required)Extensive experience in applying statistical tools to draw robust conclusions from complex datasets (required)Fluency in tools, frameworks, and methodologies instrumental for reproducible researchExperience with best practices in software development (version control, documentation, unit/integration testing)Experience with high-performance cloud computing environments and computational workflowsStrong analytical and problem-solving abilities, excellent communication and interpersonal skillsCollaborative and detail-oriented approach to efficient performance across multiple teams and projects in a highly matrixed environmentEEO StatementVerve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
Recruitment & Staffing AgenciesVerve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.#J-18808-Ljbffr