University of California - San Francisco
IND Computational Chemist/Adjunct Professor Series*
University of California - San Francisco, San Francisco, California, United States, 94199
Application WindowOpen date:
May 30, 2023Next review date:
Thursday, Jun 29, 2023 at 11:59pm (Pacific Time)Apply by this date to ensure full consideration by the committee.Final date:
Saturday, Nov 30, 2024 at 11:59pm (Pacific Time)Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.Position descriptionIND Computational Chemist/Adjunct Professor SeriesThe Institute for Neurodegenerative Diseases (IND) at the University of California, San Francisco (UCSF) is seeking a computational/theoretical chemist to join the IND's drug discovery programs in Alzheimer's disease, frontotemporal dementia, Parkinson's disease, Creutzfeldt-Jakob disease, and others. The director of the IND is Nobel Laureate Dr. Stanley Prusiner.The successful candidate will work with the drug discovery team as a computational chemist to identify and validate cellular high-throughput screening hits. For molecules in the lead optimization phase, the candidate should be able to influence and accelerate creative molecular design using modern computational tools and approaches.He or she will possess an expert-level understanding of medicinal chemistry principles, including the optimization of properties favorable for a CNS therapeutic. He or she is expected to work closely with medicinal chemists at the IND, have excellent communication skills, and work well in a team environment.QUALIFICATIONSPhD in Chemistry or a closely related fieldA strong track record of creative problem solving and scientific achievementA high level of expertise with quantum mechanical and other computational techniques to understand the conformational and stereoelectronic properties of small moleculesA strong interest in conformational analysis and the ability to provide examples of how insights into conformation can lead to improved biological activityProficiency with force field-based molecular dynamics methods to study the role of structure and conformational mobility of proteins for the purpose of drug designAn understanding of the physical chemistry of ligand design and binding thermodynamics with experience docking small molecules with associated proteinsApplicants should possess excellent leadership, organizational, communication, and interpersonal skillsPreference will be given to candidates with strong oral and written communication skillsThis is a full-time position with excellent benefits. Salary is dependent upon experience.Interested applicants should submit curriculum vitae with a list of publications, cover letter, a research summary (4-page max. including figures), and contact information for three professional references.Please apply online at
https://aprecruit.ucsf.edu/JPF04544The posted UC salary scales set the minimum pay determined by rank and step at appointment. See Table 5. The minimum base salary range for this position is $106,900-$284,100. This position includes membership in the health sciences compensation plan ( https://ucop.edu/academic-personnel-programs/_files/apm/apm-670.pdf ) which provides for eligibility for additional compensation.*Rank will be commensurate with background, experience, and work history.Application RequirementsDocument requirementsCurriculum Vitae - with a list of publications. CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).Cover LetterStatement of Research - 4-page max. including figuresStatement of Teaching (Optional)Statement of Contributions to Diversity - Please see the following page for more details: Contributions to Diversity StatementMisc / Additional (Optional)Reference requirements3 required (contact information only)Campus InformationAs a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy found here:
https://policy.ucop.edu/doc/5000695/SARS-CoV-2_Covid-19 .UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.Job locationSan Francisco, CA
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May 30, 2023Next review date:
Thursday, Jun 29, 2023 at 11:59pm (Pacific Time)Apply by this date to ensure full consideration by the committee.Final date:
Saturday, Nov 30, 2024 at 11:59pm (Pacific Time)Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.Position descriptionIND Computational Chemist/Adjunct Professor SeriesThe Institute for Neurodegenerative Diseases (IND) at the University of California, San Francisco (UCSF) is seeking a computational/theoretical chemist to join the IND's drug discovery programs in Alzheimer's disease, frontotemporal dementia, Parkinson's disease, Creutzfeldt-Jakob disease, and others. The director of the IND is Nobel Laureate Dr. Stanley Prusiner.The successful candidate will work with the drug discovery team as a computational chemist to identify and validate cellular high-throughput screening hits. For molecules in the lead optimization phase, the candidate should be able to influence and accelerate creative molecular design using modern computational tools and approaches.He or she will possess an expert-level understanding of medicinal chemistry principles, including the optimization of properties favorable for a CNS therapeutic. He or she is expected to work closely with medicinal chemists at the IND, have excellent communication skills, and work well in a team environment.QUALIFICATIONSPhD in Chemistry or a closely related fieldA strong track record of creative problem solving and scientific achievementA high level of expertise with quantum mechanical and other computational techniques to understand the conformational and stereoelectronic properties of small moleculesA strong interest in conformational analysis and the ability to provide examples of how insights into conformation can lead to improved biological activityProficiency with force field-based molecular dynamics methods to study the role of structure and conformational mobility of proteins for the purpose of drug designAn understanding of the physical chemistry of ligand design and binding thermodynamics with experience docking small molecules with associated proteinsApplicants should possess excellent leadership, organizational, communication, and interpersonal skillsPreference will be given to candidates with strong oral and written communication skillsThis is a full-time position with excellent benefits. Salary is dependent upon experience.Interested applicants should submit curriculum vitae with a list of publications, cover letter, a research summary (4-page max. including figures), and contact information for three professional references.Please apply online at
https://aprecruit.ucsf.edu/JPF04544The posted UC salary scales set the minimum pay determined by rank and step at appointment. See Table 5. The minimum base salary range for this position is $106,900-$284,100. This position includes membership in the health sciences compensation plan ( https://ucop.edu/academic-personnel-programs/_files/apm/apm-670.pdf ) which provides for eligibility for additional compensation.*Rank will be commensurate with background, experience, and work history.Application RequirementsDocument requirementsCurriculum Vitae - with a list of publications. CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).Cover LetterStatement of Research - 4-page max. including figuresStatement of Teaching (Optional)Statement of Contributions to Diversity - Please see the following page for more details: Contributions to Diversity StatementMisc / Additional (Optional)Reference requirements3 required (contact information only)Campus InformationAs a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy found here:
https://policy.ucop.edu/doc/5000695/SARS-CoV-2_Covid-19 .UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.Job locationSan Francisco, CA
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