The University of Texas MD Anderson Cancer Center
Principal/Senior/Scientist, Biomolecular Analysis
The University of Texas MD Anderson Cancer Center, Cambridge, Massachusetts, us, 02140
Job Title: Principal/Senior/Scientist, Biomolecular Analysis
Job Number:
35111
Location:
Massachusetts 02139 Cambridge,MA 02139
Job Description
In this position, you will drive the biomolecular characterization to support platform development as well as product QC. You will be focusing on bioanalytical assay development to characterize mRNA integrity, capping efficiency, modification, LNP profiles, etc. Expertise/experience in HPLC and Mass spec is highly preferred.
Responsibilities
HPLC based assay development for mRNA purity, integrity etc.
mRNA capping efficiency characterization
mRNA polyA tail analysis based on HPLC methods
mRNA integrity analysis after formulation
HPLC/MS based methods to analyze lipid composition
Analytical tool kit development to characterize long term stability of drug product
Analytical assay development and writeup for tech transfer with CDMO collaborators
Preliminary data analysis and interpretation
Meeting strict project deadlines on assigned projects
Presenting data internally in different group meetings
Assisting with other Preclinical projects as needed
Required Skills
Ph.D./M.S. in analytical chemistry, biology or related discipline
Minimum of 0-3 years (Scientist), 4-6 years (Senior scientist), 6-8+ years (Principal Scientist) of bioanalytical experience in industry
Extensive experience in HPLC, mass spec, and other analytical tools
Experience in tech transfer with CDMO is highly preferred
Strong written and oral communication skills, self-motivated, team-oriented and able to work independently
Attention to detail supported by excellent time management, organizational and communication skills
Ability to approach complex problems creatively and develop innovative solutions
Join the mission to develop innovative therapies and make a meaningful impact on patients' lives. They offer competitive compensation, comprehensive benefits, and opportunities for professional growth and development. If you are looking for a new challenge and the opportunity to contribute to cutting-edge science, please apply!
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Job Number:
35111
Location:
Massachusetts 02139 Cambridge,MA 02139
Job Description
In this position, you will drive the biomolecular characterization to support platform development as well as product QC. You will be focusing on bioanalytical assay development to characterize mRNA integrity, capping efficiency, modification, LNP profiles, etc. Expertise/experience in HPLC and Mass spec is highly preferred.
Responsibilities
HPLC based assay development for mRNA purity, integrity etc.
mRNA capping efficiency characterization
mRNA polyA tail analysis based on HPLC methods
mRNA integrity analysis after formulation
HPLC/MS based methods to analyze lipid composition
Analytical tool kit development to characterize long term stability of drug product
Analytical assay development and writeup for tech transfer with CDMO collaborators
Preliminary data analysis and interpretation
Meeting strict project deadlines on assigned projects
Presenting data internally in different group meetings
Assisting with other Preclinical projects as needed
Required Skills
Ph.D./M.S. in analytical chemistry, biology or related discipline
Minimum of 0-3 years (Scientist), 4-6 years (Senior scientist), 6-8+ years (Principal Scientist) of bioanalytical experience in industry
Extensive experience in HPLC, mass spec, and other analytical tools
Experience in tech transfer with CDMO is highly preferred
Strong written and oral communication skills, self-motivated, team-oriented and able to work independently
Attention to detail supported by excellent time management, organizational and communication skills
Ability to approach complex problems creatively and develop innovative solutions
Join the mission to develop innovative therapies and make a meaningful impact on patients' lives. They offer competitive compensation, comprehensive benefits, and opportunities for professional growth and development. If you are looking for a new challenge and the opportunity to contribute to cutting-edge science, please apply!
#J-18808-Ljbffr