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University of Texas MD Anderson Cancer Center

Postdoc - Genitourinary Medical Oncology (Guocan Wang's Lab)

University of Texas MD Anderson Cancer Center, Houston, Texas, United States, 77246


A postdoctoral position is available in the laboratory of Guocan Wang, MD, PhD, in the Department of Genitourinary Medical Oncology of the UT MD Anderson Cancer Center. We are seeking highly self-motivated candidates with a recent PhD or MD degree to study the cellular and molecular mechanisms of prostate cancer metastasis and therapy resistance to chemotherapy, targeted therapy, and immunotherapy.

Responsibilities:Designing novel projects and hypothesis-driven experimentsMaintaining detailed experiment descriptionsStandardizing and validating new methodsInterpreting resultsEntering data into statistical programs and generating figuresProviding scientific expertise in research projects involving genetic mouse models and human clinical samplesCoordinating procedures with collaboratorsPerforming technical laboratory dutiesReading, writing, and editing manuscripts and reportsAssisting with grant writing

Learning Objectives:Understanding prostate cancer biology, therapeutic agents, and metastatic castration-resistant prostate cancer (mCRPC)Studying immune tumor microenvironment focusing on myeloid-derived suppressor cells and tumor-associated macrophagesExploring cancer metabolism and epigenetics in cancer progression and therapy resistanceUsing in vitro and in vivo models for studying cancer cell function and immune tumor microenvironment

Eligibility Requirements:M.D. or Ph.D. degreeKnowledge of epigenetics, immunology, and metabolismSkills in assays related to epigenetics, immunology, and metabolismExperience with genetic mouse models and in vivo metastasis modelsFamiliarity with single-cell technology like single-cell RNA-seq

Additional Application Information:Skills in epigenetics, immunology, and metabolismExperience with genetic mouse models and in vivo metastasis modelsKnowledge of single-cell technology like single-cell RNA-seq

For more information, please refer to our recent publications (Wang Cancer Discovery 2016, Oncogene 2021, iScience 2023, Nature Comms 2023, biorxiv 10.1101/2022.05.14.491739) and funded project (DoD R01 1R01CA276235-01).

Faculty Mentor:Dr. Guocan Wang

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