Scientist - Virus Host Interactions (Arias Group)

The

Chan Zuckerberg Biohub San Francisco

( CZ Biohub SF ) is an independent nonprofit research institute that brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. CZ Biohub SF supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all. Our Vision We pursue large scientific challenges that cannot be pursued in conventional environments. We enable individual investigators to pursue their riskiest and most innovative ideas. The technologies developed at CZ Biohub San Francisco facilitate research by scientists and clinicians at our home institutions and beyond. Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an inclusive organization where all colleagues feel inspired and know their work makes an important contribution. The Opportunity The

Arias Group

at CZ Biohub San Francisco explores the molecular mechanisms of virus–host interactions in cells infected with medically relevant viruses. Our overarching objective is to reveal molecular dependencies that can be targeted for developing broad-spectrum antivirals. We actively collaborate with virology, cell biology, genomics, proteomics, microscopy, and data science teams across CZ Biohub San Francisco. We invite a dynamic and dedicated Scientist to enrich our team, someone keen to explore the intricate molecular interplay within virus-infected cells. This role is a confluence of multiomics analysis, comparative virology, and bioinformatics to uncover the mechanisms viruses use to hijack cellular machinery and identify potential targets for antiviral therapies. The application requires a

cover letter that includes your interest in this role, the contributions you are excited to make, the skills you want to strengthen on the job, your professional goals, and how this role can help you achieve them. What You'll Do Design, conduct, and analyze multiomics (transcriptomics and proteomics) experiments in virus-infected cells. Establish, optimize, and troubleshoot comparative virology experiments. Collaborate with multidisciplinary teams of virologists, cell biologists, computational microscopists, and genomics and proteomics experts. Collaborate with data sciences teams to integrate multiomic data, enhancing understanding of viral infection mechanisms. Ensure meticulous record-keeping of experimental workflows, findings, and analytical data. Disseminate findings through scientific publications and presentations at internal, local, and international conferences. Actively participate in the publication process, from manuscript preparation to submission in peer-reviewed journals and open-access platforms. Contribute to disseminating research findings by depositing software and datasets in recognized repositories. Stay updated with the latest molecular biology and multiomics techniques relevant to viral research. Provide guidance and mentorship to junior team members, fostering a nurturing learning environment. What You'll Bring Hold a Ph.D. in a relevant field with 1-2 years of post-Ph.D. experience, and at least 5 years of research experience. At least 4 years of experience in virology and general molecular biology techniques. Robust experience in RNA sequencing (bulk and single-cell) and proteomics methods. Strong relationship-, community-building and interpersonal skills. Excellent written and verbal communication skills. Excellent professional judgment, problem-solving skills, and the ability to work independently and as part of a team. Organizational skills and the flexibility to jump between projects and priorities. Nice to have - Proficiency in bioinformatics, with hands-on experience in R and/or Python programming languages. Compensation Scientist I = $100,000 - $137,500 Scientist II = $112,000 - $154,000 New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. To determine starting pay, we consider multiple job-related factors including a candidate’s skills, education and experience, market demand, business needs, and internal parity. What We Provide Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease. A collegial and collaborative environment consisting of diverse expertise. Access to collaborators, resources and facilities at our three partner universities (Stanford, UC Berkeley, and UC San Francisco) and at partner organizations in the Bay Area and beyond. Competitive compensation and benefits commensurate with experience. We offer a robust benefits program that enables the important work Biohubbers do every day. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy. The CZ Biohub Network is an equal opportunity employer committed to diversity of thought, ideas and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution.

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