Arrowhead Pharmaceuticals, Inc
Associate Scientist, CMC Analytical Development
Arrowhead Pharmaceuticals, Inc, Verona, Wisconsin, United States, 53593
Associate Scientist, CMC Analytical Development
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes.Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics.This position is in the Analytical Development (AD) Group within the CMC Manufacturing Organization. An Associate Scientist I will support method development/validation activities for new drug substances and drug products. He/She will also support testing required for GLP Toxicology and cGMP Clinical Trial material release, as well as stability studies. This position reports to either AD Management or Senior AD staff.Responsibilities:Know and adhere to cGMP policies and procedures and relevant SOPs.Work closely with team members to provide accurate analytical results in support of new and ongoing projects.Work with supervision to meet project timelines and deliverables.Perform testing of samples to support batch release and stability studies.Learn and perform portions of analytical techniques, such as HPLC, GC, FTIR, UV/Vis, LC/MS, KF, etc.Assist with the design and initiation for development of analytical methods and improvement of existing ones to support all stages of drug development process.Train and participate in evaluation and interpretation of scientific data and provide the significance of such.Assist in the design and execution of routine experiments.Participate in analysis of data/results and interpret outcome of experiments and assist in determining appropriate follow-up.Compile data tables of results and certificate of analysis, develop stability reports.Calibrate, maintain, and troubleshoot simple analytical equipment.Other duties as assigned.Requirements:B.S. in Chemistry (or related area of study).Entry level with 1-3 years of experience working in a chemistry laboratory setting.Familiar with analytical instrumentation, test methodology/validations, data acquisition systems, and cGMP policies and practices.Ability to correctly analyze data/results and interpret outcome of experiments and to propose appropriate follow-up.Strong attention to detail.Works well with others and in a team environment.Can be flexible with changing priorities.Arrowhead provides competitive salaries and an excellent benefit package.All applicants must have authorization to work in the US for a company.
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Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes.Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics.This position is in the Analytical Development (AD) Group within the CMC Manufacturing Organization. An Associate Scientist I will support method development/validation activities for new drug substances and drug products. He/She will also support testing required for GLP Toxicology and cGMP Clinical Trial material release, as well as stability studies. This position reports to either AD Management or Senior AD staff.Responsibilities:Know and adhere to cGMP policies and procedures and relevant SOPs.Work closely with team members to provide accurate analytical results in support of new and ongoing projects.Work with supervision to meet project timelines and deliverables.Perform testing of samples to support batch release and stability studies.Learn and perform portions of analytical techniques, such as HPLC, GC, FTIR, UV/Vis, LC/MS, KF, etc.Assist with the design and initiation for development of analytical methods and improvement of existing ones to support all stages of drug development process.Train and participate in evaluation and interpretation of scientific data and provide the significance of such.Assist in the design and execution of routine experiments.Participate in analysis of data/results and interpret outcome of experiments and assist in determining appropriate follow-up.Compile data tables of results and certificate of analysis, develop stability reports.Calibrate, maintain, and troubleshoot simple analytical equipment.Other duties as assigned.Requirements:B.S. in Chemistry (or related area of study).Entry level with 1-3 years of experience working in a chemistry laboratory setting.Familiar with analytical instrumentation, test methodology/validations, data acquisition systems, and cGMP policies and practices.Ability to correctly analyze data/results and interpret outcome of experiments and to propose appropriate follow-up.Strong attention to detail.Works well with others and in a team environment.Can be flexible with changing priorities.Arrowhead provides competitive salaries and an excellent benefit package.All applicants must have authorization to work in the US for a company.
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