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University of Texas MD Anderson Cancer Center

Postdoctoral Fellow - Thoracic Head & Neck Medical Oncology - Kurie Laboratory

University of Texas MD Anderson Cancer Center, Houston, Texas, United States, 77246


The Kurie Laboratory in the Department of Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer Center, seeks to fill multiple postdoctoral positions. Our research focuses on the molecular mechanisms by which lung cancer cells generate a pro-metastatic tumor microenvironment, with three complementary areas of investigation: (1) a tumor cell-derived collagen modifying enzyme called lysyl hydroxylase 2 (LH2) that functions as a nodal regulator of fibrosis and immunosuppression; (2) Golgi-directed secretory processes driven by oncogene-induced transcriptional programs; and (3) epithelial-to-mesenchymal transition as a driver of fibrosis and immunosuppression in the tumor microenvironment.

LEARNING OBJECTIVESPostdoctoral fellows will benefit from training in model development and characterization, including 2- and 3-dimensional cell culture models and autochthonous and orthotopic mouse models that recapitulate features of the TME in human cancers and translate those findings to clinical and molecularly annotated human tumor tissue banks. Fellows will have educational and mentoring opportunities (e.g., pilot funding, grant-writing courses, and teaching and mentoring experience in our summer undergraduate and graduate internship programs) and extensive opportunities to gain presentation skills at weekly Kurie lab meetings, monthly departmental joint lab meetings, monthly meetings for our programmatic research groups (NCI-funded SPORE, CPRIT-funded MIRA), and annual conferences (e.g., Keystone, Gordon, Cold Spring Harbor, AACR).

ELIGIBILITY REQUIREMENTSIndividuals who have completed a Ph.D. and have training relevant to the position. Qualified individuals will demonstrate the potential for research as evidenced by their peer-reviewed publications and funding. Background in cancer biology and expertise in the design and execution of cell culture and in vivo experiments that incorporate a variety of molecular and cellular techniques is desirable.

POSITION INFORMATIONMD Anderson offers full-time postdoc positions with a

salary ranging from $64,000 to $76,000 , depending on the number of years of postgraduate experience. MD Anderson trainee compensation also includes:Paid medical benefits (zero premium) starting on the first day for trainees who work 30 or more hours per weekGroup dental, vision, life, AD&D, and disability coveragePaid education, vacation, and sick leavePaid institutional holidays, wellness leave, childcare leave, and other paid leave programsTeachers Retirement System defined-benefit pension plan and two voluntary retirement plansEmployer-paid life, AD&D, and an illness-related reduced salary pay programHealth Savings Account and Dependent Care Reimbursement flexible spending accountsFertility benefitsState of Texas longevity payExtensive wellness, fitness, employee health programs, and employee resource groups

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