Associate Scientist/Engineer II

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As an Associate Scientist / Engineer 1 in Illumina’s Array Development Group, you will play an integral role in developing next generation –omic Array based assays for diverse research and applied markets.You will work as part of a fast paced, multi-disciplinary team focused on the enhancement of current, and development of new biochemical assays to understand the presence of different -omic traits on Illumina’s proprietary BeadArray technology.Job Responsibilities:Develop, characterize and optimize assay protocols and HW.Recognize potential problems, understand and troubleshoot assays and associated HW.Plan, conduct, analyze, interpret, and report recommendations based on tested experimental results.Conduct experiments and analyze data to support a robust supply of key components of the Infinium Assay.Develop analytical test methods to QC and understand capability of assay HW, and consumable components accurately and precisely.Develop hypothesis and statistically relevant data sets to prove correlations between physical and biochemical metrics.Analyze large complex data sets with statistical methodology.Participate in fast paced multidisciplinary development and troubleshooting teams.Conduct focused research under general direction of supervisor and drive projects.Support the testing of new Array scanner and assay automation software.Keep a laboratory notebook, write reports and prepare presentations.Become an expert in Illumina’s BeadArray assays including, but not limited to, Infinium Genotyping, Methylation, and Copy number variation.Deliver results in a fast-paced, results orientated, product development environment.Perform other duties as assigned.Qualifications

Required Skills and Experience:MSc or BSc in Bioengineering, Chemistry (analytical /physical), Biochemistry, Mechanical Engineering or related field with a minimum 7 years’ working experience in an industrial laboratory.PhD in Bioengineering, Chemistry (analytical /physical), Biochemistry, molecular biology or related field with an applied or application specific focus and a minimum 1 year of industrial experience.Demonstrated ability to develop analytical test methods to quantify inputs and outputs of key process steps.Hands-on experience with development and optimization of workflow / HW for biochemical assays.Demonstrated ability to develop QC test methods to validate HW for genomic assays.Practical experience with design, planning and execution of system / workflow level verification and validation.Practical experienced with physical characterization metrology (topology, surface energy, fluid dynamics etc).Proven record of troubleshooting assay processes to deliver root cause and robust fixes.Experienced in molecular biology methods for nucleic acid analysis and manipulation including purification, amplification, labeling, hybridization for both DNA and RNA.Excellent verbal/written communication and interpersonal skills.Flexible and adaptable.Analytical, detail-oriented, organized, takes initiative, and self-motivated.Record of process driven approach to experimental design and troubleshooting, including understanding of DOE and statistical analysis / scripting software such as JMP and R.Technical understanding of SNP genotyping analysis tools a benefit.Excellent lab notebook and documentation skills.Preferred Skills and Experience:Additional Information

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