Senior Staff Scientist

We are looking for a Senior Staff Scientist with a passion for connectomics and sequencing to lead a team project to map cortical circuits from the synaptic level in the mouse brain.The Senior Staff Scientist will work with a collaborative team of academic, staff, and industrial researchers on FISSEQ (Fluorescent in situ sequencing) Technology. The Senior Scientist will manage the Wyss component of our IARPA Machine Intelligence from Cortical Networks (MICrONS) IARPA project, including administration and supervising a large team of Scientists, Postdocs, Engineers, and Technicians at the Wyss. The Senior Scientist will also coordinate with IARPA, collaborators, and partners. The project is an effort between the Wyss Institute, Harvard Medical School, MIT, Cold Spring Harbor Labs, and Columbia University. In addition to management responsibilities, there is a significant component of bench work in FISSEQ development.Reporting to the Lead Senior Staff Scientist in Synthetic Biology; specific goals will include developing research lines in FISSEQ, and addressing limitations in the current methods and protocols. The candidate will be primarily responsible for developing FISSEQ in tissue sections and optimization with Proximity Ligation and transgenic mouse models. In addition, the candidate will investigate, modify and/or develop new protocols, procedures, or techniques to accelerate the completion of research goals. Develop new commercially valuable technology in the field of synthetic biology. Biological experimentation in synthetic biology and sequencing and development of image analysis and software algorithms. Oversee the software design and architecture; and provide guidance to multiple development teams. The candidate will identify resources in the Wyss community and beyond to approach research challenges; will conduct laboratory research, mentor and supervise the efforts of students and fellows; will collaborate with faculty and other researchers, acting as an expert in a specialized area; will participate in writing research proposals and reports to funding agencies, providing critical data, figures or information for grant and patent submissions; will write and collaborate with faculty and other researchers on manuscripts, abstracts, and other publications of research findings; will interact regularly with Core and Associate Institute faculty and Institute staff; will present research results at Wyss internal and external meetings. The candidate will train others on research methodology as well as the tools and approaches used to perform the research and collect, analyze and present the data to the research team and collaborators. General laboratory responsibilities are also required, such as maintaining budgets, equipment, supplies, and reporting laboratory results.Qualifications

PhD in Biology or related area is required. At least 4 years of experience in molecular biology or related experience is required. Strong experience in synthetic biology, genetics, molecular biology protocols or related experience is a must.Additional Information

All your information will be kept confidential according to EEO guidelines.

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